In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA

DnaA, the replication initiation protein in bacteria, is an AAA+ ATPase that binds and hydrolyzes ATP and exists in a heterogeneous population of ATP-DnaA and ADP-DnaA. DnaA binds cooperatively to the origin of replication and several other chromosomal regions, and functions as a transcription facto...

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Veröffentlicht in:	PLoS genetics 2015-05, Vol.11 (5), p.e1005258-e1005258
Hauptverfasser:	Smith, Janet L, Grossman, Alan D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphate - metabolism Bacillus subtilis - genetics Bacteria Bacterial proteins Bacterial Proteins - genetics Bacteriology Binding Sites Deoxyribonucleic acid DNA DNA - genetics DNA Replication - genetics DNA sequencing DNA-Binding Proteins - genetics DNA-Binding Proteins - isolation & purification E coli Genes Genome, Bacterial Genomes Genomics Identification and classification Methods Nucleotides - genetics Nucleotides - metabolism Physiological aspects Protein binding Protein Binding - genetics Proteins Transcription factors
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