Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction

The evolutionary divergence of mitochondrial ribosomes from their bacterial and cytoplasmic ancestors has resulted in reduced RNA content and the acquisition of mitochondria-specific proteins. The mitochondrial ribosomal protein of the small subunit 34 (MRPS34) is a mitochondria-specific ribosomal p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS genetics 2015-03, Vol.11 (3), p.e1005089-e1005089
Hauptverfasser: Richman, Tara R, Ermer, Judith A, Davies, Stefan M K, Perks, Kara L, Viola, Helena M, Shearwood, Anne-Marie J, Hool, Livia C, Rackham, Oliver, Filipovska, Aleksandra
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!