Mmp1 processing of the PDF neuropeptide regulates circadian structural plasticity of pacemaker neurons

In the Drosophila brain, the neuropeptide PIGMENT DISPERSING FACTOR (PDF) is expressed in the small and large Lateral ventral neurons (LNvs) and regulates circadian locomotor behavior. Interestingly, PDF immunoreactivity at the dorsal terminals changes across the day as synaptic contacts do as a res...

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Veröffentlicht in:	PLoS genetics 2014-10, Vol.10 (10), p.e1004700-e1004700
Hauptverfasser:	Depetris-Chauvin, Ana, Fernández-Gamba, Agata, Gorostiza, E Axel, Herrero, Anastasia, Castaño, Eduardo M, Ceriani, M Fernanda
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Behavior Behavior, Animal Biology and Life Sciences Brain Circadian rhythm Circadian Rhythm - genetics Circadian rhythms Drosophila Drosophila melanogaster Drosophila Proteins - genetics Experiments Genetic aspects Genetic regulation Genetic research Human health and pathology Insects Life Sciences Matrix Metalloproteinase 1 - genetics Motor Activity - genetics Neuronal Plasticity - genetics Neurons Neurons - metabolism Neurons - physiology Neurons and Cognition Neuropeptides Neuropeptides - genetics Physiological aspects Research and Analysis Methods
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