Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development

Histone demethylases have emerged as important players in developmental processes. Jumonji domain containing-3 (Jmjd3) has been identified as a key histone demethylase that plays a critical role in the regulation of gene expression; however, the in vivo function of Jmjd3 in embryonic development rem...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2014-07, Vol.10 (7), p.e1004524-e1004524
Hauptverfasser:	Li, Qingtian, Wang, Helen Y, Chepelev, Iouri, Zhu, Qingyuan, Wei, Gang, Zhao, Keji, Wang, Rong-Fu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology and Life Sciences Cell Differentiation - genetics Deoxyribonucleic acid DNA DNA Helicases - biosynthesis DNA methylation Embryonic development Epigenetic inheritance Epigenetics Experiments Gene expression Gene Expression Regulation, Developmental Jumonji Domain-Containing Histone Demethylases - genetics Jumonji Domain-Containing Histone Demethylases - metabolism Lung - embryology Lung - growth & development Lung - metabolism Lysine Methylation Mice Mortality Nuclear Proteins - biosynthesis Premature birth Promoter Regions, Genetic Proteins Pulmonary Surfactant-Associated Protein B - biosynthesis Respiratory distress syndrome Surfactants Thyroid Nuclear Factor 1 Transcription factors Transcription Factors - biosynthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!