zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration

Mechanisms that enable injury responses to prompt regenerative outgrowth are not well understood. Planarians can regenerate essentially any tissue removed by wounding, even after decapitation, due to robust regulation of adult pluripotent stem cells of the neoblast population. Formation of pole sign...

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Veröffentlicht in:	PLoS genetics 2014-07, Vol.10 (7), p.e1004452-e1004452
Hauptverfasser:	Vásquez-Doorman, Constanza, Petersen, Christian P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology and Life Sciences Cell Differentiation Experiments Gene expression Gene Expression Regulation, Developmental Genetic aspects Head - growth & development Helminth Proteins - genetics Hypothesis testing Physiological aspects Planarians - genetics Platyhelminthes Pluripotent Stem Cells Regeneration - genetics Research and Analysis Methods Signal Transduction - genetics Stem cell research Stem cells Tail - growth & development Transcription Factors Values Wnt Proteins - genetics
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