The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation

The Ewing sarcoma family of tumors (EFT) is a group of highly malignant small round blue cell tumors occurring in children and young adults. We report here the largest genomic survey to date of 101 EFT (65 tumors and 36 cell lines). Using a combination of whole genome sequencing and targeted sequenc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2014-07, Vol.10 (7), p.e1004475
Hauptverfasser:	Brohl, Andrew S, Solomon, David A, Chang, Wendy, Wang, Jianjun, Song, Young, Sindiri, Sivasish, Patidar, Rajesh, Hurd, Laura, Chen, Li, Shern, Jack F, Liao, Hongling, Wen, Xinyu, Gerard, Julia, Kim, Jung-Sik, Lopez Guerrero, Jose Antonio, Machado, Isidro, Wai, Daniel H, Picci, Piero, Triche, Timothy, Horvai, Andrew E, Miettinen, Markku, Wei, Jun S, Catchpool, Daniel, Llombart-Bosch, Antonio, Waldman, Todd, Khan, Javed
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antigens, Nuclear - genetics Biology and Life Sciences Cancer Care and treatment Cell Line, Tumor Child Child, Preschool Diagnosis Disease-Free Survival DNA sequencing Ewing's sarcoma Experiments Female Gene Deletion Gene expression Genetic aspects Genetic research Genome, Human Genomes High-Throughput Nucleotide Sequencing Humans Infant Male Medical prognosis Medical research Medicine and Health Sciences Metastasis Mutation Mutation - genetics Neoplasm Proteins - genetics Nucleotide sequencing Sarcoma, Ewing - etiology Sarcoma, Ewing - genetics Sarcoma, Ewing - pathology Tumor proteins Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!