Evolution of the division of labor between genes and enzymes in the RNA world

The RNA world is a very likely interim stage of the evolution after the first replicators and before the advent of the genetic code and translated proteins. Ribozymes are known to be able to catalyze many reaction types, including cofactor-aided metabolic transformations. In a metabolically complex...

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Veröffentlicht in:	PLoS computational biology 2014-12, Vol.10 (12), p.e1003936-e1003936
Hauptverfasser:	Boza, Gergely, Szilágyi, András, Kun, Ádám, Santos, Mauro, Szathmáry, Eörs
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymmetry Biological Evolution Biology and Life Sciences Computational Biology Computer and Information Sciences DNA Replication - genetics Enzymes Gene expression Genes Genetic research Grants Models, Genetic Physiological aspects RNA - genetics RNA - metabolism RNA sequencing RNA, Catalytic - genetics RNA, Catalytic - metabolism Scholarships & fellowships Transfer RNA
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