Use of Loop Diuretics is Associated with Increased Mortality in Patients with Suspected Coronary Artery Disease, but without Systolic Heart Failure or Renal Impairment: An Observational Study Using Propensity Score Matching

Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long term safety, and several observational reports have indicated adverse effects. We sought to...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0124611-e0124611
Hauptverfasser:	Schartum-Hansen, Hall, Løland, Kjetil H, Svingen, Gard F T, Seifert, Reinhard, Pedersen, Eva R, Nordrehaug, Jan E, Bleie, Øyvind, Ebbing, Marta, Berge, Christ, Nilsen, Dennis W T, Nygård, Ottar
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angina Angina pectoris Angiography Cardiology Cardiovascular disease Clinical trials Confidence intervals Coronary artery Coronary artery disease Coronary Artery Disease - mortality Coronary vessels Diuretics Edema Family medical history Female Heart diseases Heart failure Heart Failure, Systolic - mortality Hospitals Humans Hypertension Impairment Male Medical imaging Middle Aged Mortality Observational studies Observational Studies as Topic Patients Population Randomization Renal failure Renal function Renal Insufficiency - mortality Safety Science Sodium Potassium Chloride Symporter Inhibitors - adverse effects Sodium Potassium Chloride Symporter Inhibitors - therapeutic use Standard deviation Studies Systematic review Variables Ventricle
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