The Remedial Efficacy of Spirulina platensis versus Chromium-Induced Nephrotoxicity in Male Sprague-Dawley Rats

This study was conducted to investigate the possible protective effect of Spirulina platensis against chromium-induced nephrotoxicity. A total of 36 adult male Sprague-Dawley rats were divided into 4 equal groups (Gps). Gp1 served as control, rats of Gps 2, 3, and 4 were exposed to Spirulina platens...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6), p.e0126780
Hauptverfasser:	Elshazly, M O, Abd El-Rahman, Sahar S, Morgan, Ashraf M, Ali, Merhan E
Format:	Artikel
Sprache:	eng
Schlagworte:	Alterations Animals Antioxidants Atrophy Biomarkers - metabolism Body Weight - drug effects Catalase Catalase - metabolism Cell cycle Cell proliferation Chromates Chromium Chromium - blood Chromium plating Creatinine Cyanobacteria Deoxyribonucleic acid DNA DNA - metabolism Drinking water Epithelium Gene expression Glutathione - metabolism Hyperplasia Immunohistochemistry Kidney - drug effects Kidney - pathology Kidney Diseases - blood Kidney Diseases - chemically induced Kidney Diseases - drug therapy Kidneys Lipids Male Malondialdehyde - metabolism Markers Organ Size - drug effects Oxidative Stress Pathology Ploidies Ploidy Potassium Proliferating cell nuclear antigen Proliferating Cell Nuclear Antigen - metabolism Protective Agents - pharmacology Protective Agents - therapeutic use Rats Rats, Sprague-Dawley Renal function Rodents Sodium Sodium dichromate Spirulina Spirulina - chemistry Spirulina platensis Stainless steel Toxicity Urea Veterinary medicine Wood preservatives
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