Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human African trypanosomiasis

The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense. Our principle aim was to develop a prototype lateral flow test that m...

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Veröffentlicht in:	PLoS neglected tropical diseases 2014-07, Vol.8 (7), p.e2976-e2976
Hauptverfasser:	Sullivan, Lauren, Fleming, Jennifer, Sastry, Lalitha, Mehlert, Angela, Wall, Steven J, Ferguson, Michael A J
Format:	Artikel
Sprache:	eng
Schlagworte:	African trypanosomiasis Antigens Biology and Life Sciences Cohort Studies Diagnosis Enzyme-Linked Immunosorbent Assay - methods Humans Infections Medicine and Health Sciences Parasites Physiological aspects Reagent Kits, Diagnostic - parasitology Trypanosoma brucei gambiense Trypanosomiasis, African - diagnosis Trypanosomiasis, African - immunology Trypanosomiasis, African - parasitology Variant Surface Glycoproteins, Trypanosoma - immunology
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