Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate

There is evidence that stem cells and their progeny play a role in the development of the prostate. Although stem cells are also considered to give rise to differentiated progeny in the adult prostate epithelium ex vivo, the cohort of adult prostate stem cells in vivo as well as the mechanisms by wh...

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Veröffentlicht in:PloS one 2015-05, Vol.10 (5), p.e0128489-e0128489
Hauptverfasser: Pignon, Jean-Christophe, Grisanzio, Chiara, Carvo, Ingrid, Werner, Lillian, Regan, Meredith, Wilson, E Lynette, Signoretti, Sabina
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Sprache:eng
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