Identification of 4-Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH) as a Candidate Serum Autoantibody Target for Kawasaki Disease

Kawasaki disease (KD), an acute vasculitis that preferentially affects coronary arteries, is still the leading cause of acquired heart disease in children. Although the involvement of immune system malfunction in the onset of KD is suggested, its etiology still remains to be clarified. We investigat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0128189-e0128189
Hauptverfasser:	Matsunaga, Atsuko, Harita, Yutaka, Shibagaki, Yoshio, Shimizu, Nobutaka, Shibuya, Kazuhiko, Ono, Hiroshi, Kato, Hitoshi, Sekine, Takashi, Sakamoto, Naoko, Igarashi, Takashi, Hattori, Seisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde Oxidoreductases - blood Aldehyde Oxidoreductases - immunology Analysis Animals Antibodies Antigens Arteries Arthritis Autoantibodies Autoantibodies - blood Autoantibodies - immunology Autoantigens - blood Autoantigens - immunology Autoimmune diseases Biochemistry Cardiomyocytes Cardiovascular disease Care and treatment Child Child, Preschool Children Children & youth Childrens health Coronary artery disease Coronary vessels Dehydrogenase Dehydrogenases Enzyme-linked immunosorbent assay Etiology Female Genes Genetic aspects Genomes Genomics Heart Heart diseases HEK293 Cells Human Umbilical Vein Endothelial Cells Humans Immune system Immunoglobulins Immunohistochemistry Infant Inflammatory diseases Kawasaki disease Kawasaki syndrome Kinases Light chains Male Medicine Metabolism Mucocutaneous lymph node syndrome Mucocutaneous Lymph Node Syndrome - blood Mucocutaneous Lymph Node Syndrome - diagnosis Mucocutaneous Lymph Node Syndrome - immunology Multiple sclerosis Mutation Myocytes Myocytes, Cardiac - immunology Myocytes, Cardiac - metabolism Myosin Myosin Light Chains - immunology Myosin Light Chains - metabolism Neutrophils Oxidoreductases Pathogenesis Patients Pediatrics Pharmaceutical sciences Physiological aspects Proteomics Rats Reactivity Spots Vasculitis Veins & arteries Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!