The microRNA Expression Profile in Donation after Cardiac Death (DCD) Livers and Its Ability to Identify Primary Non Function

Donation after cardiac death (DCD) livers are marginal organs for transplant and their use is associated with a higher risk of primary non function (PNF) or early graft dysfunction (EGD). The aim was to determine if microRNA (miRNA) was able to discriminate between DCD livers of varying clinical out...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0127073-e0127073
Hauptverfasser:	Khorsandi, Shirin Elizabeth, Quaglia, Alberto, Salehi, Siamak, Jassem, Wayel, Vilca-Melendez, Hector, Prachalias, Andreas, Srinivasan, Parthi, Heaton, Nigel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Algorithms Analysis Apoptosis Arrays Aspartate Aminotransferases - blood Aspartate transaminase Bioinformatics Biology Biopsy Care and treatment Cell cycle Complications and side effects Computation Computer applications Data analysis Data processing Death Diagnostic systems Gene expression Genomics Heart diseases Humans Hypoglycemia Hypoxia Influence Ischemia Liver Liver - metabolism Liver Transplantation - methods Liver transplants Metabolism MicroRNA MicroRNAs MicroRNAs - genetics Middle Aged miRNA Organs Perfusion Predictions Protein turnover Ribonucleic acid RNA Rodents Signal transduction Signaling Studies Tissue and Organ Procurement - methods Tissue Donors Transaminase Transcriptome - genetics Transplants & implants
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