Aberrant function of learning and cognitive control networks underlie inefficient cognitive flexibility in anorexia nervosa: a cross-sectional fMRI study

People with Anorexia Nervosa exhibit difficulties flexibly adjusting behaviour in response to environmental changes. This has previously been attributed to problematic behavioural shifting, characterised by a decrease in fronto-striatal activity. Additionally, alterations of instrumental learning, w...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0124027-e0124027
Hauptverfasser:	Lao-Kaim, Nick P, Fonville, Leon, Giampietro, Vincent P, Williams, Steven C R, Simmons, Andrew, Tchanturia, Kate
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Adolescent Adult Alterations Anorexia Anorexia nervosa Anorexia Nervosa - pathology Anorexia Nervosa - physiopathology Biomedical research Blood Body mass index Brain Mapping Brain research Case-Control Studies Clinical trials Cognition Cognitive ability Community Corpus Striatum - pathology Corpus Striatum - physiopathology Cortex (cingulate) Cortex (frontal) Cortex (parietal) Cross-Sectional Studies Eating disorders Environmental changes Executive Function Feedback Female Females Flexibility Frontal gyrus Frontal Lobe - pathology Frontal Lobe - physiopathology Functional magnetic resonance imaging Gyrus Cinguli - pathology Gyrus Cinguli - physiopathology Human behavior Humans Learning Magnetic resonance Magnetic Resonance Imaging Medical imaging Mental disorders Mental health care Neostriatum Nerve Net - pathology Nerve Net - physiopathology Neural circuitry Neuroimaging Neuropsychological Tests Neurosciences NMR Nuclear magnetic resonance Observations Parietal Lobe - pathology Parietal Lobe - physiopathology Psychiatry Psychological aspects Studies Substrates Superior parietal lobule
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