Expression profiling of human basophils: modulation by cytokines and secretagogues

Human basophils are an accessible participant of the human allergic reaction. There is natural variation in various functional endpoints and in signaling molecule expression but there has been only a limited effort to place this information in the context of mRNA expression profiles. This study exam...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0126435-e0126435
1. Verfasser:	MacGlashan, Jr, Donald
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Asthma Atopy Basophils Basophils - drug effects Basophils - immunology Basophils - metabolism Cell division Cluster Analysis Computational Biology Cytokines Cytokines - metabolism Cytokines - pharmacology DNA microarrays Food allergies Gene expression Gene Expression Profiling Gene Expression Regulation - drug effects Genotype & phenotype Glucose Health aspects Human behavior Humans Hypersensitivity Immunoglobulin E Immunoglobulin E - immunology Immunoglobulins Interleukin 2 Interleukin 3 Interleukin 5 Kinases Leukocytes (basophilic) Nerve growth factor Phosphorylation Physiological aspects Signal transduction Signaling Signatures Stimuli Studies Transcriptome Viability
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