Lumican is overexpressed in lung adenocarcinoma pleural effusions

Adenocarcinoma (AdC) is the most common lung cancer subtype and is often associated with pleural effusion (PE). Its poor prognosis is attributable to diagnostic delay and lack of effective treatments and there is a pressing need in discovering new biomarkers for early diagnosis or targeted therapies...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0126458-e0126458
Hauptverfasser:	Cappellesso, Rocco, Millioni, Renato, Arrigoni, Giorgio, Simonato, Francesca, Caroccia, Brasilina, Iori, Elisabetta, Guzzardo, Vincenza, Ventura, Laura, Tessari, Paolo, Fassina, Ambrogio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma of Lung Angiogenesis Biomarkers Cancer Cell culture Cell Line, Tumor Chondroitin Sulfate Proteoglycans - metabolism Conditioning Diagnosis Diagnostic systems Female Fibroblasts Fluid Fluids Gene expression Humans Immunoblotting Immunohistochemistry Keratan Sulfate - metabolism Kinases Lumican Lung cancer Lung diseases Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medicine Metabolism Neoplasm Grading Neoplasm Staging Pathology Physiological aspects Plasma Pleural effusion Pleural Effusion, Malignant - metabolism Prognosis Proteins Proteome Proteomics Proteomics - methods Signal transduction Stroma Surgery Tumors
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