Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy

The absorption spectrum of light is known to be a "molecular fingerprint" that enables analysis of the molecular type and its amount. It would be useful to measure the absorption spectrum in single cell in order to investigate the cellular status. However, cells are too thin for their abso...

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Veröffentlicht in:	PloS one 2015-05, Vol.10 (5), p.e0125733-e0125733
Hauptverfasser:	Arai, Yoshiyuki, Yamamoto, Takayuki, Minamikawa, Takeo, Takamatsu, Tetsuro, Nagai, Takeharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Absorption spectra Animals Biodiversity Biological properties Biological samples Biopsy Cells (Biology) Chlorocebus aethiops COS Cells Electromagnetic absorption Fingerprinting HeLa Cells Humans Light Light absorption Light reflection Mammalian cells Mice Microscopy Microscopy - methods NIH 3T3 Cells PC12 Cells Principal Component Analysis Principal components analysis Proteins Rats Single-Cell Analysis - methods Spatial analysis Spatial discrimination Spatial resolution Species diversity Spectrum analysis
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