The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats

The Lao PDR, as did most countries of the Mekong Region, embarked on a pandemic vaccine initiative to counter the threat posed by influenza A(H1N1)pdm09. Overall, estimated vaccine coverage of the Lao population was 14%, with uptake in targeted health care workers and pregnant women 99% and 41%, res...

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Veröffentlicht in:PloS one 2015-04, Vol.10 (4), p.e0121717-e0121717
Hauptverfasser: Xeuatvongsa, Anonh, Mirza, Sara, Winter, Christian, Feldon, Keith, Vongphrachanh, Phengta, Phonekeo, Darouny, Denny, Justin, Khanthamaly, Viengphone, Kounnavong, Bounheuang, Lylianou, Doualy, Phousavath, Sisouphane, Norasingh, Sisouveth, Boutta, Nao, Olsen, Sonja, Bresee, Joseph, Moen, Ann, Corwin, Andrew
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container_end_page e0121717
container_issue 4
container_start_page e0121717
container_title PloS one
container_volume 10
creator Xeuatvongsa, Anonh
Mirza, Sara
Winter, Christian
Feldon, Keith
Vongphrachanh, Phengta
Phonekeo, Darouny
Denny, Justin
Khanthamaly, Viengphone
Kounnavong, Bounheuang
Lylianou, Doualy
Phousavath, Sisouphane
Norasingh, Sisouveth
Boutta, Nao
Olsen, Sonja
Bresee, Joseph
Moen, Ann
Corwin, Andrew
description The Lao PDR, as did most countries of the Mekong Region, embarked on a pandemic vaccine initiative to counter the threat posed by influenza A(H1N1)pdm09. Overall, estimated vaccine coverage of the Lao population was 14%, with uptake in targeted health care workers and pregnant women 99% and 41%, respectively. Adverse Events Following Immunization accounted for only 6% of survey driven, reported vaccination experiences, with no severe consequences or deaths. Public acceptability of the vaccine campaign was high (98%). Challenges to vaccine deployment included: 1) no previous experience in fielding a seasonal influenza vaccine, 2) safety and efficacy concerns, and 3) late arrival of vaccine 10 months into the pandemic. The Lao success in surmounting these hurdles was in large measure attributed to the oversight assigned the National Immunization Program, and national sensitivities in responding to the avian influenza A(H5N1) crisis in the years leading up to the pandemic. The Lao "lessons learned" from pandemic vaccine deployment are made even more relevant four years on, given the many avian influenza strains circulating in the region, all with pandemic potential.
doi_str_mv 10.1371/journal.pone.0121717
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subjects Adolescent
Adult
Aged
Aged, 80 and over
Attitude of Health Personnel
Avian flu
Avian influenza
Child
Child, Preschool
Disease control
Disease prevention
Epidemics
Epidemiology
Female
Government agencies
Health care
Health surveillance
Humans
Immunization
Influenza
Influenza A
Influenza A Virus, H1N1 Subtype - immunology
Influenza Vaccines
Influenza, Human - epidemiology
Influenza, Human - prevention & control
Laboratories
Laos
Male
Mass Vaccination
Medical personnel
Middle Aged
Pandemics
Patient Acceptance of Health Care
Pregnancy
Pregnant women
Public health
Surveys
Time Factors
Vaccination
Vaccines
Viruses
Young Adult
title The Lao Experience in Deploying Influenza A(H1N1)pdm09 Vaccine: Lessons Made Relevant in Preparing for Present Day Pandemic Threats
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