CD161 Expression Defines a Th1/Th17 Polyfunctional Subset of Resident Memory T Lymphocytes in Bronchoalveolar Cells

Alveolar resident memory T cells (T(RM)) comprise a currently uncharacterized mixture of cell subpopulations. The CD3(+)CD161(+) T cell subpopulation resides in the liver, intestine and skin, but it has the capacity for tissue migration; however, the presence of resident CD3(+)CD161(+) T cells in th...

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Veröffentlicht in:	PloS one 2015-04, Vol.10 (4), p.e0123591-e0123591
Hauptverfasser:	Gonzalez, Yolanda, Herrera, María Teresa, Juárez, Esmeralda, Salazar-Lezama, Miguel Angel, Bobadilla, Karen, Torres, Martha
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Bank clearinghouses Blood Bronchoalveolar Lavage Fluid Bronchus CD3 antigen CD4 antigen CD8 antigen Cell migration Cell surface Cytokines Healthy Volunteers Helper cells Humans Immune response Immunologic Memory Immunological memory Immunophenotyping Interferon Interferon-gamma - immunology Interleukin Interleukin 17 Interleukin-17 - immunology Intestine Ionomycin Leukocyte migration Leukocytes (mononuclear) Liver Lungs Lymphocytes Lymphocytes T Memory cells NK Cell Lectin-Like Receptor Subfamily B - immunology Peripheral blood mononuclear cells Skin Subpopulations T cells Th1 Cells - immunology Th17 Cells - immunology γ-Interferon
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