Molecular Dynamics Simulations of the Human Glucose Transporter GLUT1

Glucose transporters (GLUTs) provide a pathway for glucose transport across membranes. Human GLUTs are implicated in devastating diseases such as heart disease, hyper- and hypo-glycemia, type 2 diabetes and cancer. The human GLUT1 has been recently crystalized in the inward-facing open conformation....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-04, Vol.10 (4), p.e0125361
1. Verfasser:	Park, Min-Sun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Binding Sites Biochemistry Biological Transport Blood glucose Chemical properties Computer simulation Conformation Coronary artery disease Crystal structure Cytoplasm Diabetes mellitus E coli Glucose Glucose - metabolism Glucose transport Glucose transporter Glucose Transporter Type 1 - chemistry Glucose Transporter Type 1 - metabolism Heart diseases Helices Homology Humans Intracellular Ligands Membranes Molecular dynamics Molecular Dynamics Simulation Molecular interactions Mutagenesis Next-generation sequencing Permease Protein Binding Protein Structure, Secondary Protein Structure, Tertiary Residues Structural Homology, Protein Substrate Specificity Substrates Sugar Water - metabolism Xylose
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!