Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera

The GII.4 noroviruses (NoVs) are a single genotype that is responsible for over 50% of NoV gastroenteritis epidemics worldwide. However, GII.4 NoVs have been found to undergo antigenic drifts, likely selected by host herd immunity, which raises an issue for vaccine strategies against NoVs. We previo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-04, Vol.10 (4), p.e0124945-e0124945
Hauptverfasser:	Dai, Ying-Chun, Zhang, Xu-Fu, Xia, Ming, Tan, Ming, Quigley, Christina, Lei, Wen, Fang, Hao, Zhong, Weiming, Lee, Bonita, Pang, Xiaoli, Nie, Jun, Jiang, Xi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animals Antigens Antigens, Viral - chemistry Antigens, Viral - genetics Antigens, Viral - metabolism Binding Blood Group Antigens - chemistry Blood Group Antigens - metabolism Caliciviridae Infections - blood Caliciviridae Infections - immunology Caliciviridae Infections - virology Conserved Sequence Cross-reactivity Epidemics Evolution, Molecular Gastroenteritis Gastroenteritis - blood Gastroenteritis - immunology Gastroenteritis - virology Genetic Variation Herd immunity Humans Immune Sera - metabolism Immunity Immunoassays Interfaces Mice Norovirus - classification Norovirus - genetics Norovirus - immunology Vaccine development Vaccines Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!