No Additional Prognostic Value of Genetic Information in the Prediction of Vascular Events after Cerebral Ischemia of Arterial Origin: The PROMISe Study

Patients who have suffered from cerebral ischemia have a high risk of recurrent vascular events. Predictive models based on classical risk factors typically have limited prognostic value. Given that cerebral ischemia has a heritable component, genetic information might improve performance of these r...

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Veröffentlicht in:	PloS one 2015-04, Vol.10 (4), p.e0119203
Hauptverfasser:	Achterberg, Sefanja, Kappelle, L Jaap, de Bakker, Paul I W, Traylor, Matthew, Algra, Ale
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Area Under Curve Arteries - pathology Blood platelets Brain Ischemia - genetics Cardiac arrhythmia Cerebral Infarction - genetics Cerebral ischemia Confidence intervals Consortia Disease Epidemiology Female Genetics Genome-wide association studies Genome-Wide Association Study - methods Genomes Genomics Genotype Health sciences Humans Incidence Ischemia Laboratories Male Mathematical models Middle Aged Neurology Neurosurgery Patients Performance enhancement Polymorphism, Single Nucleotide - genetics Prediction models Primary care Prognosis Risk analysis Risk Factors ROC Curve Single nucleotide polymorphisms Single-nucleotide polymorphism Stroke Stroke - genetics Studies Vascular Diseases - genetics
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