Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells

The local synthesis of dopamine and its effects on insulin release have been described in isolated islets. Thus, it may be accepted that dopamine exerts an auto-paracrine regulation of insulin secretion from pancreatic beta cells. The aim of the present study is to analyze whether dopamine is a regu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2015-04, Vol.10 (4), p.e0123197-e0123197
Hauptverfasser:	Garcia Barrado, Maria Jose, Iglesias Osma, Maria Carmen, Blanco, Enrique J, Carretero Hernández, Marta, Sánchez Robledo, Virginia, Catalano Iniesta, Leonardo, Carrero, Sixto, Carretero, Jose
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Beta cells Caspase Caspase-3 Cell proliferation Cell Proliferation - drug effects Cell survival Cell Survival - drug effects Cytochemistry Dopamine Dopamine - pharmacology Glucose Glucose - pharmacology Insulin Insulin - metabolism Insulin Secretion Insulin-Secreting Cells - drug effects Insulin-Secreting Cells - metabolism Islets of Langerhans - drug effects Islets of Langerhans - metabolism Labeling Labelling Male Pancreas Pancreatic beta cells Paracrine signalling Phenols (Class of compounds) Proliferating cell nuclear antigen Rats Rats, Wistar
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!