Keratometric index obtained by Fourier-domain optical coherence tomography
To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT). The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-...
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| creator | Hua, Yanjun Stojanovic, Aleksander Utheim, Tor Paaske Chen, Xiangjun Ræder, Sten Huang, Jinhai Wang, Qinmei |
| description | To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT).
The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 39 keratoconus eyes. The total corneal powers were calculated using different keratometric indices: Kcal based on the mean calculated keratometric index, K1.3315 calculated by the keratometric index of 1.3315, and K1.3375 calculated by the keratometric index of 1.3375. In addition, the total corneal powers based on Gaussian optics formula (Kactual) were calculated.
The means for Ratio in untreated controls, post-LASIK/PRK group and keratoconus group were 1.176 ± 0.022 (95% confidence interval (CI), 1.172-1.179), 1.314 ± 0.042 (95%CI, 1.303-1.325) and 1.229 ± 0.118 (95%CI, 1.191-1.267), respectively. And the mean calculated keratometric index in untreated controls, post-LASIK/PRK group and keratoconus group were 1.3299 ± 0.00085 (95%CI, 1.3272-1.3308), 1.3242 ± 0.00171 (95%CI, 1.3238-1.3246) and 1.3277 ± 0.0046 (95%CI, 1.3263-1.3292), respectively. All the parameters were normally distributed. The differences between Kcal and Kactual, K1.3315 and Kactual, and K1.3375 and Kactual were 0.00 ± 0.11 D, 0.21 ± 0.11 D and 0.99 ± 0.12 D, respectively, in untreated controls; -0.01 ± 0.20 D, 0.85 ± 0.18 D and 1.56 ± 0.16 D, respectively, in post-LASIK/PRK group; and 0.03 ± 0.67 D, 0.56 ± 0.70 D and 1.40 ± 0.76 D, respectively, in keratoconus group.
The calculated keratometric index is negatively related to the ratio of anterior corneal curvature to posterior corneal curvature in untreated, post-LASIK/PRK, and keratoconus eyes, respectively. Using the calculated keratometric index may improve the prediction accuracies of total corneal powers in untreated controls, but not in post-LASIK/PRK and keratoconus eyes. |
| doi_str_mv | 10.1371/journal.pone.0122441 |
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| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1673954063</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A425368124</galeid><doaj_id>oai_doaj_org_article_3750f628a7ee4b3c80838252f081db46</doaj_id><sourcerecordid>A425368124</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-167220b671290d70567bc6791d3730248f2ab106feeff944cddb54ba2240de443</originalsourceid><addsrcrecordid>eNqNkltv1DAQhSMEohf4BwgiISF42MW3OM4LUlW1sFCpErdXy7Enu14l8dZ2UPff4-2m1Qb1AeXB0eQ7ZzLjk2WvMJpjWuKPazf4XrXzjethjjAhjOEn2TGuKJlxgujTg_ej7CSENUIFFZw_z45IIQRnojrOvn4Dr6LrIHqrc9sbuM1dHZXtweT1Nr9MXSz4mXFdquVuE61Wba7dCjz0GvKkdUuvNqvti-xZo9oAL8fzNPt1efHz_Mvs6vrz4vzsaqZ5ReIM85IQVPMSkwqZEhW8rDUvK2xoSRFhoiGqxog3AE1TMaaNqQtWqzQgMsAYPc3e7H03rQtyXEOQyZdWBUOcJmKxJ4xTa7nxtlN-K52y8q7g_FIqnwZpQdKyQA0nQpUArKZaIEEFKUiDBDY148nr09htqDswGvroVTsxnX7p7Uou3R_JGMK82hm8Hw28uxkgRNnZoKFtVQ9uuPtvxkVZEZLQt_-gj083UkuVBrB941JfvTOVZ4wUlAtMdluaP0Klx0BndcpMY1N9IvgwESQmwm1cqiEEufjx_f_Z699T9t0BuwLVxlVw7RCt68MUZHtQexeCh-ZhyRjJXeTvtyF3kZdj5JPs9eEFPYjuM07_ArTN-ik</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1673954063</pqid></control><display><type>article</type><title>Keratometric index obtained by Fourier-domain optical coherence tomography</title><source>Public Library of Science (PLoS) Journals Open Access</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Hua, Yanjun ; Stojanovic, Aleksander ; Utheim, Tor Paaske ; Chen, Xiangjun ; Ræder, Sten ; Huang, Jinhai ; Wang, Qinmei</creator><creatorcontrib>Hua, Yanjun ; Stojanovic, Aleksander ; Utheim, Tor Paaske ; Chen, Xiangjun ; Ræder, Sten ; Huang, Jinhai ; Wang, Qinmei</creatorcontrib><description>To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT).
The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 39 keratoconus eyes. The total corneal powers were calculated using different keratometric indices: Kcal based on the mean calculated keratometric index, K1.3315 calculated by the keratometric index of 1.3315, and K1.3375 calculated by the keratometric index of 1.3375. In addition, the total corneal powers based on Gaussian optics formula (Kactual) were calculated.
The means for Ratio in untreated controls, post-LASIK/PRK group and keratoconus group were 1.176 ± 0.022 (95% confidence interval (CI), 1.172-1.179), 1.314 ± 0.042 (95%CI, 1.303-1.325) and 1.229 ± 0.118 (95%CI, 1.191-1.267), respectively. And the mean calculated keratometric index in untreated controls, post-LASIK/PRK group and keratoconus group were 1.3299 ± 0.00085 (95%CI, 1.3272-1.3308), 1.3242 ± 0.00171 (95%CI, 1.3238-1.3246) and 1.3277 ± 0.0046 (95%CI, 1.3263-1.3292), respectively. All the parameters were normally distributed. The differences between Kcal and Kactual, K1.3315 and Kactual, and K1.3375 and Kactual were 0.00 ± 0.11 D, 0.21 ± 0.11 D and 0.99 ± 0.12 D, respectively, in untreated controls; -0.01 ± 0.20 D, 0.85 ± 0.18 D and 1.56 ± 0.16 D, respectively, in post-LASIK/PRK group; and 0.03 ± 0.67 D, 0.56 ± 0.70 D and 1.40 ± 0.76 D, respectively, in keratoconus group.
The calculated keratometric index is negatively related to the ratio of anterior corneal curvature to posterior corneal curvature in untreated, post-LASIK/PRK, and keratoconus eyes, respectively. Using the calculated keratometric index may improve the prediction accuracies of total corneal powers in untreated controls, but not in post-LASIK/PRK and keratoconus eyes.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0122441</identifier><identifier>PMID: 25886489</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adult ; Coherence ; Confidence intervals ; Cornea ; Cornea - physiopathology ; Cornea - surgery ; Curvature ; Eye ; Fourier Analysis ; Humans ; Keratoconus ; Keratoconus - physiopathology ; Keratoconus - surgery ; Keratomileusis, Laser In Situ ; Mathematical analysis ; Middle Aged ; Normal distribution ; Optical Coherence Tomography ; Optics ; Photorefractive Keratectomy ; Refraction, Ocular - physiology ; Tomography ; Tomography, Optical Coherence ; Young Adult</subject><ispartof>PloS one, 2015-04, Vol.10 (4), p.e0122441-e0122441</ispartof><rights>COPYRIGHT 2015 Public Library of Science</rights><rights>2015 Hua et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2015 Hua et al 2015 Hua et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-167220b671290d70567bc6791d3730248f2ab106feeff944cddb54ba2240de443</citedby><cites>FETCH-LOGICAL-c692t-167220b671290d70567bc6791d3730248f2ab106feeff944cddb54ba2240de443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401696/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401696/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25886489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hua, Yanjun</creatorcontrib><creatorcontrib>Stojanovic, Aleksander</creatorcontrib><creatorcontrib>Utheim, Tor Paaske</creatorcontrib><creatorcontrib>Chen, Xiangjun</creatorcontrib><creatorcontrib>Ræder, Sten</creatorcontrib><creatorcontrib>Huang, Jinhai</creatorcontrib><creatorcontrib>Wang, Qinmei</creatorcontrib><title>Keratometric index obtained by Fourier-domain optical coherence tomography</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT).
The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 39 keratoconus eyes. The total corneal powers were calculated using different keratometric indices: Kcal based on the mean calculated keratometric index, K1.3315 calculated by the keratometric index of 1.3315, and K1.3375 calculated by the keratometric index of 1.3375. In addition, the total corneal powers based on Gaussian optics formula (Kactual) were calculated.
The means for Ratio in untreated controls, post-LASIK/PRK group and keratoconus group were 1.176 ± 0.022 (95% confidence interval (CI), 1.172-1.179), 1.314 ± 0.042 (95%CI, 1.303-1.325) and 1.229 ± 0.118 (95%CI, 1.191-1.267), respectively. And the mean calculated keratometric index in untreated controls, post-LASIK/PRK group and keratoconus group were 1.3299 ± 0.00085 (95%CI, 1.3272-1.3308), 1.3242 ± 0.00171 (95%CI, 1.3238-1.3246) and 1.3277 ± 0.0046 (95%CI, 1.3263-1.3292), respectively. All the parameters were normally distributed. The differences between Kcal and Kactual, K1.3315 and Kactual, and K1.3375 and Kactual were 0.00 ± 0.11 D, 0.21 ± 0.11 D and 0.99 ± 0.12 D, respectively, in untreated controls; -0.01 ± 0.20 D, 0.85 ± 0.18 D and 1.56 ± 0.16 D, respectively, in post-LASIK/PRK group; and 0.03 ± 0.67 D, 0.56 ± 0.70 D and 1.40 ± 0.76 D, respectively, in keratoconus group.
The calculated keratometric index is negatively related to the ratio of anterior corneal curvature to posterior corneal curvature in untreated, post-LASIK/PRK, and keratoconus eyes, respectively. Using the calculated keratometric index may improve the prediction accuracies of total corneal powers in untreated controls, but not in post-LASIK/PRK and keratoconus eyes.</description><subject>Adult</subject><subject>Coherence</subject><subject>Confidence intervals</subject><subject>Cornea</subject><subject>Cornea - physiopathology</subject><subject>Cornea - surgery</subject><subject>Curvature</subject><subject>Eye</subject><subject>Fourier Analysis</subject><subject>Humans</subject><subject>Keratoconus</subject><subject>Keratoconus - physiopathology</subject><subject>Keratoconus - surgery</subject><subject>Keratomileusis, Laser In Situ</subject><subject>Mathematical analysis</subject><subject>Middle Aged</subject><subject>Normal distribution</subject><subject>Optical Coherence Tomography</subject><subject>Optics</subject><subject>Photorefractive Keratectomy</subject><subject>Refraction, Ocular - physiology</subject><subject>Tomography</subject><subject>Tomography, Optical Coherence</subject><subject>Young Adult</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNkltv1DAQhSMEohf4BwgiISF42MW3OM4LUlW1sFCpErdXy7Enu14l8dZ2UPff4-2m1Qb1AeXB0eQ7ZzLjk2WvMJpjWuKPazf4XrXzjethjjAhjOEn2TGuKJlxgujTg_ej7CSENUIFFZw_z45IIQRnojrOvn4Dr6LrIHqrc9sbuM1dHZXtweT1Nr9MXSz4mXFdquVuE61Wba7dCjz0GvKkdUuvNqvti-xZo9oAL8fzNPt1efHz_Mvs6vrz4vzsaqZ5ReIM85IQVPMSkwqZEhW8rDUvK2xoSRFhoiGqxog3AE1TMaaNqQtWqzQgMsAYPc3e7H03rQtyXEOQyZdWBUOcJmKxJ4xTa7nxtlN-K52y8q7g_FIqnwZpQdKyQA0nQpUArKZaIEEFKUiDBDY148nr09htqDswGvroVTsxnX7p7Uou3R_JGMK82hm8Hw28uxkgRNnZoKFtVQ9uuPtvxkVZEZLQt_-gj083UkuVBrB941JfvTOVZ4wUlAtMdluaP0Klx0BndcpMY1N9IvgwESQmwm1cqiEEufjx_f_Z699T9t0BuwLVxlVw7RCt68MUZHtQexeCh-ZhyRjJXeTvtyF3kZdj5JPs9eEFPYjuM07_ArTN-ik</recordid><startdate>20150417</startdate><enddate>20150417</enddate><creator>Hua, Yanjun</creator><creator>Stojanovic, Aleksander</creator><creator>Utheim, Tor Paaske</creator><creator>Chen, Xiangjun</creator><creator>Ræder, Sten</creator><creator>Huang, Jinhai</creator><creator>Wang, Qinmei</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20150417</creationdate><title>Keratometric index obtained by Fourier-domain optical coherence tomography</title><author>Hua, Yanjun ; Stojanovic, Aleksander ; Utheim, Tor Paaske ; Chen, Xiangjun ; Ræder, Sten ; Huang, Jinhai ; Wang, Qinmei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-167220b671290d70567bc6791d3730248f2ab106feeff944cddb54ba2240de443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Coherence</topic><topic>Confidence intervals</topic><topic>Cornea</topic><topic>Cornea - physiopathology</topic><topic>Cornea - surgery</topic><topic>Curvature</topic><topic>Eye</topic><topic>Fourier Analysis</topic><topic>Humans</topic><topic>Keratoconus</topic><topic>Keratoconus - physiopathology</topic><topic>Keratoconus - surgery</topic><topic>Keratomileusis, Laser In Situ</topic><topic>Mathematical analysis</topic><topic>Middle Aged</topic><topic>Normal distribution</topic><topic>Optical Coherence Tomography</topic><topic>Optics</topic><topic>Photorefractive Keratectomy</topic><topic>Refraction, Ocular - physiology</topic><topic>Tomography</topic><topic>Tomography, Optical Coherence</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hua, Yanjun</creatorcontrib><creatorcontrib>Stojanovic, Aleksander</creatorcontrib><creatorcontrib>Utheim, Tor Paaske</creatorcontrib><creatorcontrib>Chen, Xiangjun</creatorcontrib><creatorcontrib>Ræder, Sten</creatorcontrib><creatorcontrib>Huang, Jinhai</creatorcontrib><creatorcontrib>Wang, Qinmei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hua, Yanjun</au><au>Stojanovic, Aleksander</au><au>Utheim, Tor Paaske</au><au>Chen, Xiangjun</au><au>Ræder, Sten</au><au>Huang, Jinhai</au><au>Wang, Qinmei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Keratometric index obtained by Fourier-domain optical coherence tomography</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2015-04-17</date><risdate>2015</risdate><volume>10</volume><issue>4</issue><spage>e0122441</spage><epage>e0122441</epage><pages>e0122441-e0122441</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT).
The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 39 keratoconus eyes. The total corneal powers were calculated using different keratometric indices: Kcal based on the mean calculated keratometric index, K1.3315 calculated by the keratometric index of 1.3315, and K1.3375 calculated by the keratometric index of 1.3375. In addition, the total corneal powers based on Gaussian optics formula (Kactual) were calculated.
The means for Ratio in untreated controls, post-LASIK/PRK group and keratoconus group were 1.176 ± 0.022 (95% confidence interval (CI), 1.172-1.179), 1.314 ± 0.042 (95%CI, 1.303-1.325) and 1.229 ± 0.118 (95%CI, 1.191-1.267), respectively. And the mean calculated keratometric index in untreated controls, post-LASIK/PRK group and keratoconus group were 1.3299 ± 0.00085 (95%CI, 1.3272-1.3308), 1.3242 ± 0.00171 (95%CI, 1.3238-1.3246) and 1.3277 ± 0.0046 (95%CI, 1.3263-1.3292), respectively. All the parameters were normally distributed. The differences between Kcal and Kactual, K1.3315 and Kactual, and K1.3375 and Kactual were 0.00 ± 0.11 D, 0.21 ± 0.11 D and 0.99 ± 0.12 D, respectively, in untreated controls; -0.01 ± 0.20 D, 0.85 ± 0.18 D and 1.56 ± 0.16 D, respectively, in post-LASIK/PRK group; and 0.03 ± 0.67 D, 0.56 ± 0.70 D and 1.40 ± 0.76 D, respectively, in keratoconus group.
The calculated keratometric index is negatively related to the ratio of anterior corneal curvature to posterior corneal curvature in untreated, post-LASIK/PRK, and keratoconus eyes, respectively. Using the calculated keratometric index may improve the prediction accuracies of total corneal powers in untreated controls, but not in post-LASIK/PRK and keratoconus eyes.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>25886489</pmid><doi>10.1371/journal.pone.0122441</doi><oa>free_for_read</oa></addata></record> |
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| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adult Coherence Confidence intervals Cornea Cornea - physiopathology Cornea - surgery Curvature Eye Fourier Analysis Humans Keratoconus Keratoconus - physiopathology Keratoconus - surgery Keratomileusis, Laser In Situ Mathematical analysis Middle Aged Normal distribution Optical Coherence Tomography Optics Photorefractive Keratectomy Refraction, Ocular - physiology Tomography Tomography, Optical Coherence Young Adult |
| title | Keratometric index obtained by Fourier-domain optical coherence tomography |
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