Lower inter-partum interval and unhealthy life-style factors are inversely associated with n-3 essential fatty acids changes during pregnancy: a prospective cohort with Brazilian women
To analyze serum fatty acids concentrations during healthy pregnancy and evaluate whether socioeconomic, demographic, obstetric, nutritional, anthropometric and lifestyle factors are associated with their longitudinal changes. A prospective cohort of 225 pregnant women was followed in the 5th-13th,...
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| Veröffentlicht in: | PloS one 2015-03, Vol.10 (3), p.e0121151-e0121151 |
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| creator | Pinto, Thatiana J P Farias, Dayana R Rebelo, Fernanda Lepsch, Jaqueline Vaz, Juliana S Moreira, Júlia D Cunha, Geraldo M Kac, Gilberto |
| description | To analyze serum fatty acids concentrations during healthy pregnancy and evaluate whether socioeconomic, demographic, obstetric, nutritional, anthropometric and lifestyle factors are associated with their longitudinal changes.
A prospective cohort of 225 pregnant women was followed in the 5th-13th, 20th-26th and 30th-36th weeks of gestation. Serum samples were collected in each trimester of pregnancy and analyzed to determine the fatty acids composition using a high-throughput robotic direct methylation method coupled with fast gas-liquid chromatography. The independent variables comprised the subjects' socioeconomic and demographic status, obstetric history, early pregnancy body mass index (BMI), dietary and lifestyle parameters. Analyses were performed using linear mixed-effects models.
The overall absolute concentrations of fatty acids increased from the 1st to the 2nd trimester and slightly increased from the 2nd to the 3rd trimester. Early pregnancy BMI, inter-partum interval and weekly fish intake were the factors associated with changes in eicosapentaenoic + docosahexaenoic acids (EPA+DHA) and total n-3 polyunsaturated fatty acids (PUFAs). Early pregnancy BMI, age and monthly per-capita income were inversely associated with the changes in the n-6/n-3 ratio. Alcohol consumption was positively associated with the n-6/n-3 ratio.
Early pregnancy BMI was positively associated with EPA+DHA and total n-3 PUFAs, while presenting a reduced weekly fish intake and a lower inter-partum interval were associated with lower levels of n-3 PUFAs. A lower per-capita family income and a drinking habit were factors that were positively associated with a higher n-6/n-3 ratio. |
| doi_str_mv | 10.1371/journal.pone.0121151 |
| format | Article |
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A prospective cohort of 225 pregnant women was followed in the 5th-13th, 20th-26th and 30th-36th weeks of gestation. Serum samples were collected in each trimester of pregnancy and analyzed to determine the fatty acids composition using a high-throughput robotic direct methylation method coupled with fast gas-liquid chromatography. The independent variables comprised the subjects' socioeconomic and demographic status, obstetric history, early pregnancy body mass index (BMI), dietary and lifestyle parameters. Analyses were performed using linear mixed-effects models.
The overall absolute concentrations of fatty acids increased from the 1st to the 2nd trimester and slightly increased from the 2nd to the 3rd trimester. Early pregnancy BMI, inter-partum interval and weekly fish intake were the factors associated with changes in eicosapentaenoic + docosahexaenoic acids (EPA+DHA) and total n-3 polyunsaturated fatty acids (PUFAs). Early pregnancy BMI, age and monthly per-capita income were inversely associated with the changes in the n-6/n-3 ratio. Alcohol consumption was positively associated with the n-6/n-3 ratio.
Early pregnancy BMI was positively associated with EPA+DHA and total n-3 PUFAs, while presenting a reduced weekly fish intake and a lower inter-partum interval were associated with lower levels of n-3 PUFAs. A lower per-capita family income and a drinking habit were factors that were positively associated with a higher n-6/n-3 ratio.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0121151</identifier><identifier>PMID: 25822204</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Alcohol use ; Alcoholic beverages ; Anthropometry ; Birth Intervals ; Body mass ; Body Mass Index ; Body size ; Brazil ; Chromatography ; Chromatography, Gas ; Chronic illnesses ; Cohort Studies ; Demographic variables ; Demographics ; Demography ; Diabetes ; Diet ; Drinking behavior ; Epidemiology ; Fatty acids ; Fatty Acids, Essential - blood ; Female ; Fish ; Gestation ; High-Throughput Screening Assays ; Humans ; Hypertension ; Income ; Independent variables ; Life Style ; Linear Models ; Lipids ; Liquid chromatography ; Maternal & child health ; Metabolism ; Methylation ; Nutrition research ; Observatories ; Polyunsaturated fatty acids ; Pregnancy ; Pregnancy - blood ; Pregnant women ; Prenatal care ; Prospective Studies ; Public health ; Seafood ; Seafoods ; Social factors ; Socio-economic aspects ; Socioeconomic Factors ; Socioeconomics ; Studies ; Surveys and Questionnaires ; Time Factors ; Unsaturated fatty acids ; Womens health</subject><ispartof>PloS one, 2015-03, Vol.10 (3), p.e0121151-e0121151</ispartof><rights>COPYRIGHT 2015 Public Library of Science</rights><rights>2015 Pinto et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2015 Pinto et al 2015 Pinto et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-8ca42f80c22db3f6d362b79516f3e6ed1b558c39479cdd19433af77f14e1c36a3</citedby><cites>FETCH-LOGICAL-c692t-8ca42f80c22db3f6d362b79516f3e6ed1b558c39479cdd19433af77f14e1c36a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379070/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379070/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25822204$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Gonzalez-Bulnes, Antonio</contributor><creatorcontrib>Pinto, Thatiana J P</creatorcontrib><creatorcontrib>Farias, Dayana R</creatorcontrib><creatorcontrib>Rebelo, Fernanda</creatorcontrib><creatorcontrib>Lepsch, Jaqueline</creatorcontrib><creatorcontrib>Vaz, Juliana S</creatorcontrib><creatorcontrib>Moreira, Júlia D</creatorcontrib><creatorcontrib>Cunha, Geraldo M</creatorcontrib><creatorcontrib>Kac, Gilberto</creatorcontrib><title>Lower inter-partum interval and unhealthy life-style factors are inversely associated with n-3 essential fatty acids changes during pregnancy: a prospective cohort with Brazilian women</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To analyze serum fatty acids concentrations during healthy pregnancy and evaluate whether socioeconomic, demographic, obstetric, nutritional, anthropometric and lifestyle factors are associated with their longitudinal changes.
A prospective cohort of 225 pregnant women was followed in the 5th-13th, 20th-26th and 30th-36th weeks of gestation. Serum samples were collected in each trimester of pregnancy and analyzed to determine the fatty acids composition using a high-throughput robotic direct methylation method coupled with fast gas-liquid chromatography. The independent variables comprised the subjects' socioeconomic and demographic status, obstetric history, early pregnancy body mass index (BMI), dietary and lifestyle parameters. Analyses were performed using linear mixed-effects models.
The overall absolute concentrations of fatty acids increased from the 1st to the 2nd trimester and slightly increased from the 2nd to the 3rd trimester. Early pregnancy BMI, inter-partum interval and weekly fish intake were the factors associated with changes in eicosapentaenoic + docosahexaenoic acids (EPA+DHA) and total n-3 polyunsaturated fatty acids (PUFAs). Early pregnancy BMI, age and monthly per-capita income were inversely associated with the changes in the n-6/n-3 ratio. Alcohol consumption was positively associated with the n-6/n-3 ratio.
Early pregnancy BMI was positively associated with EPA+DHA and total n-3 PUFAs, while presenting a reduced weekly fish intake and a lower inter-partum interval were associated with lower levels of n-3 PUFAs. A lower per-capita family income and a drinking habit were factors that were positively associated with a higher n-6/n-3 ratio.</description><subject>Alcohol use</subject><subject>Alcoholic beverages</subject><subject>Anthropometry</subject><subject>Birth Intervals</subject><subject>Body mass</subject><subject>Body Mass Index</subject><subject>Body size</subject><subject>Brazil</subject><subject>Chromatography</subject><subject>Chromatography, Gas</subject><subject>Chronic illnesses</subject><subject>Cohort Studies</subject><subject>Demographic variables</subject><subject>Demographics</subject><subject>Demography</subject><subject>Diabetes</subject><subject>Diet</subject><subject>Drinking behavior</subject><subject>Epidemiology</subject><subject>Fatty acids</subject><subject>Fatty Acids, Essential - blood</subject><subject>Female</subject><subject>Fish</subject><subject>Gestation</subject><subject>High-Throughput Screening Assays</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Income</subject><subject>Independent variables</subject><subject>Life Style</subject><subject>Linear Models</subject><subject>Lipids</subject><subject>Liquid chromatography</subject><subject>Maternal & child health</subject><subject>Metabolism</subject><subject>Methylation</subject><subject>Nutrition research</subject><subject>Observatories</subject><subject>Polyunsaturated fatty acids</subject><subject>Pregnancy</subject><subject>Pregnancy - blood</subject><subject>Pregnant women</subject><subject>Prenatal care</subject><subject>Prospective Studies</subject><subject>Public health</subject><subject>Seafood</subject><subject>Seafoods</subject><subject>Social factors</subject><subject>Socio-economic aspects</subject><subject>Socioeconomic Factors</subject><subject>Socioeconomics</subject><subject>Studies</subject><subject>Surveys and Questionnaires</subject><subject>Time Factors</subject><subject>Unsaturated fatty acids</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11v0zAUhiMEYmPwDxBYQkJwkeKPxEm4QBoTH5UmTeLr1nLtk9STaxfbaSm_jJ-Hu3bTinaBcpHYec577PecUxRPCZ4Q1pA3l34MTtrJ0juYYEIJqcm94ph0jJacYnb_1vdR8SjGS4xr1nL-sDiidUspxdVx8efcryEg4xKEcilDGhe7xUpaJJ1Go5uDtGm-Qdb0UMa0sYB6qZIPEckAmV5BiGA3SMbolZEJNFqbNEeuZAhiBJdMFutlSplRRkek5tINEJEeg3EDWgYYnHRq8xbJvPBxCSqZFSDl5z6kndr7IH8ba6RDa78A97h40Esb4cn-fVJ8__jh29nn8vzi0_Ts9LxUvKOpbJWsaN9iRamesZ5rxums6WrCewYcNJnVdatYVzWd0pp0FWOyb5qeVEAU45KdFM93ukvro9ibHgXhvOF1rkOXiemO0F5eimUwCxk2wksjrjZ8GET21SgLomo4rjVpOVFNRTFv647UTKpt9TTHLGu922cbZwvQKnsXpD0QPfzjzFwMfiUq1nS4wVng1V4g-J8jxCQWJiqwVjrw49W5W8pagpuMvvgHvft2e2qQ-QLG9T7nVVtRcVqRDjPO2Dbt5A4qPxoWRuUO7U3ePwh4fRCQmQS_0iDHGMX065f_Zy9-HLIvb7G71o3ejsl4Fw_Bageq3G8xQH9jMsFiO2DXbojtgIn9gOWwZ7cLdBN0PVHsL2DCIy4</recordid><startdate>20150330</startdate><enddate>20150330</enddate><creator>Pinto, Thatiana J P</creator><creator>Farias, Dayana R</creator><creator>Rebelo, Fernanda</creator><creator>Lepsch, Jaqueline</creator><creator>Vaz, Juliana S</creator><creator>Moreira, Júlia D</creator><creator>Cunha, Geraldo M</creator><creator>Kac, Gilberto</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20150330</creationdate><title>Lower inter-partum interval and unhealthy life-style factors are inversely associated with n-3 essential fatty acids changes during pregnancy: a prospective cohort with Brazilian women</title><author>Pinto, Thatiana J P ; Farias, Dayana R ; Rebelo, Fernanda ; Lepsch, Jaqueline ; Vaz, Juliana S ; Moreira, Júlia D ; Cunha, Geraldo M ; Kac, Gilberto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-8ca42f80c22db3f6d362b79516f3e6ed1b558c39479cdd19433af77f14e1c36a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Alcohol use</topic><topic>Alcoholic beverages</topic><topic>Anthropometry</topic><topic>Birth Intervals</topic><topic>Body mass</topic><topic>Body Mass Index</topic><topic>Body size</topic><topic>Brazil</topic><topic>Chromatography</topic><topic>Chromatography, Gas</topic><topic>Chronic illnesses</topic><topic>Cohort Studies</topic><topic>Demographic variables</topic><topic>Demographics</topic><topic>Demography</topic><topic>Diabetes</topic><topic>Diet</topic><topic>Drinking behavior</topic><topic>Epidemiology</topic><topic>Fatty acids</topic><topic>Fatty Acids, Essential - blood</topic><topic>Female</topic><topic>Fish</topic><topic>Gestation</topic><topic>High-Throughput Screening Assays</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Income</topic><topic>Independent variables</topic><topic>Life Style</topic><topic>Linear Models</topic><topic>Lipids</topic><topic>Liquid chromatography</topic><topic>Maternal & child health</topic><topic>Metabolism</topic><topic>Methylation</topic><topic>Nutrition research</topic><topic>Observatories</topic><topic>Polyunsaturated fatty acids</topic><topic>Pregnancy</topic><topic>Pregnancy - blood</topic><topic>Pregnant women</topic><topic>Prenatal care</topic><topic>Prospective Studies</topic><topic>Public health</topic><topic>Seafood</topic><topic>Seafoods</topic><topic>Social factors</topic><topic>Socio-economic aspects</topic><topic>Socioeconomic Factors</topic><topic>Socioeconomics</topic><topic>Studies</topic><topic>Surveys and Questionnaires</topic><topic>Time Factors</topic><topic>Unsaturated fatty acids</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pinto, Thatiana J P</creatorcontrib><creatorcontrib>Farias, Dayana R</creatorcontrib><creatorcontrib>Rebelo, Fernanda</creatorcontrib><creatorcontrib>Lepsch, Jaqueline</creatorcontrib><creatorcontrib>Vaz, Juliana S</creatorcontrib><creatorcontrib>Moreira, Júlia D</creatorcontrib><creatorcontrib>Cunha, Geraldo M</creatorcontrib><creatorcontrib>Kac, Gilberto</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pinto, Thatiana J P</au><au>Farias, Dayana R</au><au>Rebelo, Fernanda</au><au>Lepsch, Jaqueline</au><au>Vaz, Juliana S</au><au>Moreira, Júlia D</au><au>Cunha, Geraldo M</au><au>Kac, Gilberto</au><au>Gonzalez-Bulnes, Antonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lower inter-partum interval and unhealthy life-style factors are inversely associated with n-3 essential fatty acids changes during pregnancy: a prospective cohort with Brazilian women</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2015-03-30</date><risdate>2015</risdate><volume>10</volume><issue>3</issue><spage>e0121151</spage><epage>e0121151</epage><pages>e0121151-e0121151</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To analyze serum fatty acids concentrations during healthy pregnancy and evaluate whether socioeconomic, demographic, obstetric, nutritional, anthropometric and lifestyle factors are associated with their longitudinal changes.
A prospective cohort of 225 pregnant women was followed in the 5th-13th, 20th-26th and 30th-36th weeks of gestation. Serum samples were collected in each trimester of pregnancy and analyzed to determine the fatty acids composition using a high-throughput robotic direct methylation method coupled with fast gas-liquid chromatography. The independent variables comprised the subjects' socioeconomic and demographic status, obstetric history, early pregnancy body mass index (BMI), dietary and lifestyle parameters. Analyses were performed using linear mixed-effects models.
The overall absolute concentrations of fatty acids increased from the 1st to the 2nd trimester and slightly increased from the 2nd to the 3rd trimester. Early pregnancy BMI, inter-partum interval and weekly fish intake were the factors associated with changes in eicosapentaenoic + docosahexaenoic acids (EPA+DHA) and total n-3 polyunsaturated fatty acids (PUFAs). Early pregnancy BMI, age and monthly per-capita income were inversely associated with the changes in the n-6/n-3 ratio. Alcohol consumption was positively associated with the n-6/n-3 ratio.
Early pregnancy BMI was positively associated with EPA+DHA and total n-3 PUFAs, while presenting a reduced weekly fish intake and a lower inter-partum interval were associated with lower levels of n-3 PUFAs. A lower per-capita family income and a drinking habit were factors that were positively associated with a higher n-6/n-3 ratio.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>25822204</pmid><doi>10.1371/journal.pone.0121151</doi><oa>free_for_read</oa></addata></record> |
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| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1667653719 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Alcohol use Alcoholic beverages Anthropometry Birth Intervals Body mass Body Mass Index Body size Brazil Chromatography Chromatography, Gas Chronic illnesses Cohort Studies Demographic variables Demographics Demography Diabetes Diet Drinking behavior Epidemiology Fatty acids Fatty Acids, Essential - blood Female Fish Gestation High-Throughput Screening Assays Humans Hypertension Income Independent variables Life Style Linear Models Lipids Liquid chromatography Maternal & child health Metabolism Methylation Nutrition research Observatories Polyunsaturated fatty acids Pregnancy Pregnancy - blood Pregnant women Prenatal care Prospective Studies Public health Seafood Seafoods Social factors Socio-economic aspects Socioeconomic Factors Socioeconomics Studies Surveys and Questionnaires Time Factors Unsaturated fatty acids Womens health |
| title | Lower inter-partum interval and unhealthy life-style factors are inversely associated with n-3 essential fatty acids changes during pregnancy: a prospective cohort with Brazilian women |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T15%3A41%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lower%20inter-partum%20interval%20and%20unhealthy%20life-style%20factors%20are%20inversely%20associated%20with%20n-3%20essential%20fatty%20acids%20changes%20during%20pregnancy:%20a%20prospective%20cohort%20with%20Brazilian%20women&rft.jtitle=PloS%20one&rft.au=Pinto,%20Thatiana%20J%20P&rft.date=2015-03-30&rft.volume=10&rft.issue=3&rft.spage=e0121151&rft.epage=e0121151&rft.pages=e0121151-e0121151&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0121151&rft_dat=%3Cgale_plos_%3EA419036330%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1667653719&rft_id=info:pmid/25822204&rft_galeid=A419036330&rft_doaj_id=oai_doaj_org_article_47605d1861c74206859153ac1211d603&rfr_iscdi=true |