The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

The role of the human microbiome on cancer progression remains unclear. Therefore, in this study, we investigated the influence of some quorum sensing peptides, produced by diverse commensal or pathogenic bacteria, on breast cancer cell invasion and thus cancer outcome. Based on microscopy, transcri...

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Veröffentlicht in:	PloS one 2015-03, Vol.10 (3), p.e0119471-e0119471
Hauptverfasser:	De Spiegeleer, Bart, Verbeke, Frederick, D'Hondt, Matthias, Hendrix, An, Van De Wiele, Christophe, Burvenich, Christian, Peremans, Kathelijne, De Wever, Olivier, Bracke, Marc, Wynendaele, Evelien
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Animals Bacteria Bacterial Proteins - metabolism Bacterial Proteins - physiology Biofilms Breast cancer Breast Neoplasms - pathology Breastfeeding & lactation Caco-2 Cells Cancer Chick Embryo Chorioallantoic membrane Development and progression E coli Escherichia coli Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gram-negative bacteria Health sciences Hospitals Humans MCF-7 Cells Medical research Metastases Metastasis Microbiomes Microbiota - physiology Microscopy Neoplasm Invasiveness Neovascularization, Pathologic Oncology Penicillin Peptides Pharmaceutical sciences Physiology Quorum Sensing Registration Tumors Veterinary medicine
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