Point-of-care CD4 testing to inform selection of antiretroviral medications in south african antenatal clinics: a cost-effectiveness analysis

Many prevention of mother-to-child HIV transmission (PMTCT) programs currently prioritize antiretroviral therapy (ART) for women with advanced HIV. Point-of-care (POC) CD4 assays may expedite the selection of three-drug ART instead of zidovudine, but are costlier than traditional laboratory assays....

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Veröffentlicht in:	PloS one 2015-03, Vol.10 (3), p.e0117751
Hauptverfasser:	Ciaranello, Andrea L, Myer, Landon, Kelly, Kathleen, Christensen, Sarah, Daskilewicz, Kristen, Doherty, Katie, Bekker, Linda-Gail, Hou, Taige, Wood, Robin, Francke, Jordan A, Wools-Kaloustian, Kara, Freedberg, Kenneth A, Walensky, Rochelle P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Age AIDS Analysis Anti-HIV Agents - economics Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Assaying Care and treatment CD4 antigen CD4 Lymphocyte Count - economics CD4 Lymphocyte Count - methods Child Computer simulation Cost analysis Cost engineering Cost-Benefit Analysis Costs Disease transmission Economic aspects Female Gestational age Health aspects Health care Health Care Costs Highly active antiretroviral therapy HIV HIV infections HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - economics HIV Infections - transmission Human immunodeficiency virus Humans Infant Infants Infections Infectious Disease Transmission, Vertical - prevention & control Life Expectancy Life span Point-of-Care Systems - economics Pregnancy Prevention South Africa Tutu, Desmond Weaning Womens health Young Adult Zidovudine Zidovudine - economics Zidovudine - therapeutic use
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