Associations among Sebox and other MEGs and its effects on early embryogenesis

In a previous report, we identified Sebox as a new candidate maternal effect gene that is essential for embryonic development and primarily impacts the two-cell (2C) stage. The present study was conducted to determine the mechanism of action for Sebox in this capacity, as shown by changes in the exp...

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Veröffentlicht in:	PloS one 2015-02, Vol.10 (2), p.e0115050-e0115050
Hauptverfasser:	Park, Min-Woo, Kim, Kyeoung-Hwa, Kim, Eun-Young, Lee, Su-Yeon, Ko, Jung-Jae, Lee, Kyung-Ah
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Animals Basic Helix-Loop-Helix Transcription Factors - genetics Deoxyribonucleic acid Developmental stages DNA DNA methylation Egg Proteins - genetics Embryogenesis Embryonic Development Embryonic growth stage Embryos Female Gene expression Gene Expression Regulation, Developmental Gene Knockdown Techniques Genes Genetic Markers - genetics Genomes Genomics Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Laboratory animals Life sciences Male Metaphase Mice Mice, Inbred ICR Oocytes Pregnancy Ribonucleic acid RNA RNA Interference RNA Stability RNA, Messenger - chemistry RNA, Messenger - genetics RNA, Messenger - metabolism RNA-mediated interference Transcription Transcription factors Transcription, Genetic Zygote - metabolism
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