Multi-regional investigation of the relationship between functional MRI blood oxygenation level dependent (BOLD) activation and GABA concentration

Several recent studies have reported an inter-individual correlation between regional GABA concentration, as measured by MRS, and the amplitude of the functional blood oxygenation level dependent (BOLD) response in the same region. In this study, we set out to investigate whether this coupling gener...

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Veröffentlicht in:	PloS one 2015-02, Vol.10 (2), p.e0117531-e0117531
Hauptverfasser:	Harris, Ashley D, Puts, Nicolaas A J, Anderson, Brian A, Yantis, Steven, Pekar, James J, Barker, Peter B, Edden, Richard A E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acoustic Stimulation Activation Adult Auditory Cortex - metabolism Blood Brain - physiology Brain Mapping Correlation Correlation analysis Cortex (auditory) Cortex (frontal) Cortex (occipital) Cortex (somatosensory) Female Functional magnetic resonance imaging GABA gamma-Aminobutyric Acid - analysis Humans Magnetic Resonance Imaging Male Medical imaging Menstruation Mental task performance Metabolism Motor task performance Occipital lobe Oxygen - blood Oxygenation Prefrontal cortex Radiology Receptive field Saccadic eye movements Science Sensorimotor Cortex - metabolism Sensory integration Short term memory Somatosensory cortex Spectrum analysis Studies Visual cortex Visual stimuli White noise γ-Aminobutyric acid
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