Pancreatic and pancreatic-like microbial proteases accelerate gut maturation in neonatal rats

Postnatal gut maturation in neonatal mammals, either at natural weaning or after precocious inducement, is coinciding with enhanced enzymes production by exocrine pancreas. Since the involvement of enzymes in gut functional maturation was overlooked, the present study aimed to investigate the role o...

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Veröffentlicht in:	PloS one 2015-02, Vol.10 (2), p.e0116947-e0116947
Hauptverfasser:	Prykhodko, Olena, Pierzynowski, Stefan G, Nikpey, Elham, Arevalo Sureda, Ester, Fedkiv, Olexandr, Weström, Björn R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amylases Animals Animals, Newborn Biologi Biological Sciences Biology Blood Body Weight - drug effects Bovine serum albumin Cattle Digestive system Digestive tract Dose-Response Relationship, Drug Enterocytes Enzymes Exposure Female Fetuses Gastric Acid - metabolism Gastric Acid/secretion Gastric juice Gastroenterology & hepatology Gastroentérologie & hépatologie Gastrointestinal tract Hogs Human health sciences Hydrolases Immunoglobulin G Immunoglobulin G - blood Intestine Intestines - drug effects Intestines - growth & development Intestines/drug effects/growth & development Lactalbumin Lactase Lipase Macromolecules Mammals Maturation Microorganisms Milk Natural Sciences Naturvetenskap Neonates Newborn babies Organ Size - drug effects Organs Pancreas Pancreas - enzymology Peptide Hydrolases - pharmacology Permeability Proteins Rats Rats, Sprague-Dawley Rodents Sciences de la santé humaine Secretion Serum albumin Serum Albumin, Bovine - analysis Small intestine Structure-function relationships Suckling behavior Sus scrofa Trypsin Weaning Zoologi Zoology
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