Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

Pulmonary deposited carbon nanotubes (CNTs) are cleared very slowly from the lung, but there is limited information on how CNTs interact with the lung tissue over time. To address this, three different multiwalled CNTs were intratracheally instilled into female C57BL/6 mice: one short (850 nm) and t...

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Veröffentlicht in:	PloS one 2015-01, Vol.10 (1), p.e0116481-e0116481
Hauptverfasser:	Købler, Carsten, Poulsen, Sarah S, Saber, Anne T, Jacobsen, Nicklas R, Wallin, Håkan, Yauk, Carole L, Halappanavar, Sabina, Vogel, Ulla, Qvortrup, Klaus, Mølhave, Kristian
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Alveoli Animals Bronchoalveolar lavage Bronchoalveolar Lavage Fluid - chemistry Bronchus Carbon Carbon nanotubes Crystal structure Crystallinity Electron microscopy Enclosures Endocytosis Exposure Female Gene expression Health sciences House mouse Immunology Inflammation Leukocytes (eosinophilic) Lung - drug effects Lung - ultrastructure Lungs Macrophages Mice Mice, Inbred C57BL Microscopy, Electron, Transmission - methods Nanotechnology Nanotubes Nanotubes, Carbon - toxicity Nanotubes, Carbon - ultrastructure Neutrophils Particle Size Pneumonia Pulmonary Eosinophilia - chemically induced Studies Time Factors Toxicology Transmission electron microscopy
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