Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors

In recent years, the increasing prevalence of obesity and obesity-related co-morbidities fostered intensive research in the field of adipose tissue biology. To further unravel molecular mechanisms of adipose tissue function, genetic tools enabling functional studies in vitro and in vivo are essentia...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-12, Vol.9 (12), p.e116288-e116288
Hauptverfasser:	Uhrig-Schmidt, Silke, Geiger, Matthias, Luippold, Gerd, Birk, Gerald, Mennerich, Detlev, Neubauer, Heike, Grimm, Dirk, Wolfrum, Christian, Kreuz, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adiponectin Adiponectin - genetics Adipose tissue Adipose Tissue - virology Animal genetic engineering Animals Biology and life sciences Body fat Carrier Proteins - genetics Carrier Proteins - metabolism Cytomegalovirus Dependovirus - genetics Expression vectors Gene transfer Gene Transfer Techniques Genes Genetic engineering Genetic modification Genetic Therapy - methods Genetic Vectors Genetically modified organisms Genomes Green Fluorescent Proteins - analysis Health aspects In vivo methods and tests Infectious diseases Lipids Mammals Medicine and Health Sciences Metabolism Mice MicroRNAs Molecular modelling Nutrition Obesity Perilipin-1 Phosphoproteins - genetics Phosphoproteins - metabolism Promoter Regions, Genetic Rodents Tissues Transcription Transcription (Genetics) Transgenic animals Vectors (Biology) Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!