Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC

The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation. The MHC is generally divided into subregions (classes I, II and III) containing genes of similar function across species, but with di...

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Veröffentlicht in:	PloS one 2014-12, Vol.9 (12), p.e114631
Hauptverfasser:	Jaratlerdsiri, Weerachai, Deakin, Janine, Godinez, Ricardo M, Shan, Xueyan, Peterson, Daniel G, Marthey, Sylvain, Lyons, Eric, McCarthy, Fiona M, Isberg, Sally R, Higgins, Damien P, Chong, Amanda Y, John, John St, Glenn, Travis C, Ray, David A, Gongora, Jaime
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Alligators Alligators and Crocodiles - genetics Alligators and Crocodiles - virology Analysis Animals Antigen presentation Aquatic reptiles Artificial chromosomes Bacterial artificial chromosomes Biochemistry Bioinformatics Biology and Life Sciences Biotechnology Birds Chromosomes Chromosomes, Artificial, Bacterial - genetics Clusters Contig Mapping Crocodiles Crocodylidae Crocodylus porosus Gene clusters Gene order Gene sequencing Genes Genes, MHC Class I - genetics Genes, MHC Class II - genetics Genomes Genomics Immunity Life Sciences Major histocompatibility complex Molecular biology Plant pathology Reptiles & amphibians Retroelements - genetics Retroviridae - genetics Saline water Science Six gene Species Specificity Synteny Vertebrates Zebrafish
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