The four-herb Chinese medicine ANBP enhances wound healing and inhibits scar formation via bidirectional regulation of transformation growth factor pathway

The four-herb Chinese medicine ANBP is a pulverized mixture of four herbs including Agrimonia Eupatoria (A), Nelumbo Nucifera Gaertn (N), Boswellia Carteri (B) and Pollen Typhae Angustifoliae (P). The combination of the four herbs was first described in Chinese canonical medicine about 2000 years ag...

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Veröffentlicht in:	PloS one 2014-12, Vol.9 (12), p.e112274
Hauptverfasser:	Hou, Qian, He, Wen-Jun, Hao, Hao-Jie, Han, Qing-Wang, Chen, Li, Dong, Liang, Liu, Jie-Jie, Li, Xiang, Zhang, Ya-Jing, Ma, Ying-Zhi, Han, Wei-Dong, Fu, Xiao-Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrimonia eupatoria Analgesia Animal models Animals Bone morphogenetic proteins Boswellia Cell cycle Chinese medicine Chromatography Cicatrix, Hypertrophic - genetics Cicatrix, Hypertrophic - pathology Cicatrix, Hypertrophic - physiopathology Cicatrix, Hypertrophic - prevention & control Collagen Collagen - metabolism Collagens Drugs, Chinese Herbal - pharmacology Ear - pathology Ear - physiopathology Eutrophication Extracellular Matrix - drug effects Extracellular Matrix - metabolism Fibroblasts Gene expression Gene Expression Regulation - drug effects Granulation Growth factors Hemostasis Hemostatics Herbal medicine Herbs Hospitals Inflammation Inflammation Mediators - metabolism Laboratory animals Medical research Medicine Medicine and Health Sciences mRNA Nelumbo nucifera Pain perception Pathways Pharmaceuticals Pollen Powders Quality control Rabbits Regulation Scars Signal transduction Signal Transduction - drug effects Skin Smad protein Smad Proteins - metabolism Smad2 protein Temperature Transformation Transforming growth factor Transforming Growth Factor beta1 - metabolism Transforming growth factor-b1 Transforming growth factors Trauma Typha angustifolia Wound care Wound healing Wound Healing - drug effects
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