The proapoptotic protein BNIP3 interacts with VDAC to induce mitochondrial release of endonuclease G

BNIP3 is a proapoptotic protein that induces cell death through a mitochondria-mediated pathway. We reported previously that mitochondrial localization of BNIP3 and translocation of EndoG from mitochondria to the nucleus are critical steps of the BNIP3 pathway. It is not clear, however, that how BNI...

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Veröffentlicht in:PloS one 2014-12, Vol.9 (12), p.e113642-e113642
Hauptverfasser: Zhang, Xiaosha, Bian, Xiuwu, Kong, Jiming
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Sprache:eng
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