Hypoxia in vascular networks: a complex system approach to unravel the diabetic paradox

In this work we model the extent of hypoxia in the diabetic retina as a function of the area affected by vessel disruption. We find two regimes that differ on the ratio between the area of disrupted vasculature and the area of tissue in hypoxia. In the first regime the hypoxia is localized in the vi...

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Veröffentlicht in:PloS one 2014-11, Vol.9 (11), p.e113165-e113165
Hauptverfasser: Gandica, Yérali, Schwarz, Tobias, Oliveira, Orlando, Travasso, Rui D M
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Sprache:eng
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