Atrophy and other potential factors affecting long term deep brain stimulation response: a case series
To describe three DBS cases which presented with new side effects or loss of benefit from stimulation after long-term follow-up and to discuss the potential contributing factors. A University of Florida (UF) database (INFORM) search was performed, identifying three patients, two Parkinson's dis...
Gespeichert in:
| Veröffentlicht in: | PloS one 2014-10, Vol.9 (10), p.e111561-e111561 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e111561 |
|---|---|
| container_issue | 10 |
| container_start_page | e111561 |
| container_title | PloS one |
| container_volume | 9 |
| creator | Martinez-Ramirez, Daniel Morishita, Takashi Zeilman, Pamela R Peng-Chen, Zhongxing Foote, Kelly D Okun, Michael S |
| description | To describe three DBS cases which presented with new side effects or loss of benefit from stimulation after long-term follow-up and to discuss the potential contributing factors.
A University of Florida (UF) database (INFORM) search was performed, identifying three patients, two Parkinson's disease (PD) and one Essential Tremor (ET), with an unexpected change in long-term programming thresholds as compared to initial evaluation. Clinical follow-up, programming, imaging studies, and lead measurements were reviewed. The UF Institutional Review Board (IRB) approved this study.
A substantial increase in the 3rd ventricular width (120%), Evans index (6%), ventricular index (5%), and cella media index (17%) was uncovered. A change in thresholds across lead contacts with a decrease in current densities as well as a relative lateral change of lead location was also observed. Hardware-related complications, lead migration, and impedance variability were not identified.
Potential factors contributing to long-term side effects should be examined during a DBS troubleshooting assessment. Clinicians should be aware that in DBS therapy there is delivery of electricity to a changing brain, and atrophy may possibly affect DBS programming settings as part of long-term follow-up. |
| doi_str_mv | 10.1371/journal.pone.0111561 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1619083804</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A417145056</galeid><doaj_id>oai_doaj_org_article_d08061ff96294e6db2ba620fdba60903</doaj_id><sourcerecordid>A417145056</sourcerecordid><originalsourceid>FETCH-LOGICAL-c758t-51a924702b5cd9a16aa4b13b8756392d7c0eaf53abf02f597312abdcbc7ca5c03</originalsourceid><addsrcrecordid>eNqNk1uL1DAUx4so7jr6DUQDgujDjLk0vfggDIuXgYUFb6_hNE1mMqRNN0nF_fZmnO4ylX2QQhKS3_nn5N9zsuw5wSvCSvJu70bfg10NrlcrTAjhBXmQnZOa0WVBMXt4sj7LnoSwx5izqigeZ2eUswLzuj7P9Dp6N-xuEPQtcnGnPBpcVH00YJEGGZ0PCLRWMpp-i6xLQ1S-Q61SA2o8mB6FaLrRQjSuR16FlFBQ7xEgCUGhoLxR4Wn2SIMN6tk0L7Ifnz5-v_iyvLz6vLlYXy5lyau45ARqmpeYNly2NZACIG8Ia6qSF6ymbSmxAs0ZNBpTzeuSEQpNKxtZSuASs0X28qg7WBfEZFEQpCA1rliF80RsjkTrYC8GbzrwN8KBEX83nN8K8NFIq0SLK1wQreuC1rkq2oY2kNzUbZpwjVnS-jDdNjadamWyzYOdic5PerMTW_dL5DRlRGgSeDMJeHc9qhBFZ4JU1kKv3HjIm2JMc1bWCX31D3r_6yZqC-kBptcu3SsPomKdk5LkHCcnF9nqHip9reqMTPWkTdqfBbydBSQmqt9xC2MIYvPt6_-zVz_n7OsTdqfAxl1wdjyUUpiD-RGU3oXglb4zmWBxaIdbN8ShHcTUDinsxekPugu6rX_2B3AVBZ8</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1619083804</pqid></control><display><type>article</type><title>Atrophy and other potential factors affecting long term deep brain stimulation response: a case series</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Martinez-Ramirez, Daniel ; Morishita, Takashi ; Zeilman, Pamela R ; Peng-Chen, Zhongxing ; Foote, Kelly D ; Okun, Michael S</creator><contributor>Gross, Robert E.</contributor><creatorcontrib>Martinez-Ramirez, Daniel ; Morishita, Takashi ; Zeilman, Pamela R ; Peng-Chen, Zhongxing ; Foote, Kelly D ; Okun, Michael S ; Gross, Robert E.</creatorcontrib><description>To describe three DBS cases which presented with new side effects or loss of benefit from stimulation after long-term follow-up and to discuss the potential contributing factors.
A University of Florida (UF) database (INFORM) search was performed, identifying three patients, two Parkinson's disease (PD) and one Essential Tremor (ET), with an unexpected change in long-term programming thresholds as compared to initial evaluation. Clinical follow-up, programming, imaging studies, and lead measurements were reviewed. The UF Institutional Review Board (IRB) approved this study.
A substantial increase in the 3rd ventricular width (120%), Evans index (6%), ventricular index (5%), and cella media index (17%) was uncovered. A change in thresholds across lead contacts with a decrease in current densities as well as a relative lateral change of lead location was also observed. Hardware-related complications, lead migration, and impedance variability were not identified.
Potential factors contributing to long-term side effects should be examined during a DBS troubleshooting assessment. Clinicians should be aware that in DBS therapy there is delivery of electricity to a changing brain, and atrophy may possibly affect DBS programming settings as part of long-term follow-up.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0111561</identifier><identifier>PMID: 25360599</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Aged ; Aging ; Atrophy ; Biology and Life Sciences ; Brain ; Brain - pathology ; Cerebral Ventricles - pathology ; Comparative analysis ; Complications ; Data bases ; Deep Brain Stimulation ; Electric contacts ; Electrodes ; Female ; Humans ; Identification methods ; Lead ; Magnetic Resonance Imaging ; Maintenance ; Male ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Migration ; Movement disorders ; Neurodegenerative diseases ; Neuroimaging ; Neurology ; Neurosurgery ; NMR ; Nuclear magnetic resonance ; Organ Size ; Parkinson's disease ; Parkinsons disease ; Patients ; Programming ; Risk Factors ; Side effects ; Stimulation ; Surgery ; Thresholds ; Time Factors ; Treatment Outcome ; Tremor ; Ventricle</subject><ispartof>PloS one, 2014-10, Vol.9 (10), p.e111561-e111561</ispartof><rights>COPYRIGHT 2014 Public Library of Science</rights><rights>2014 Martinez-Ramirez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2014 Martinez-Ramirez et al 2014 Martinez-Ramirez et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c758t-51a924702b5cd9a16aa4b13b8756392d7c0eaf53abf02f597312abdcbc7ca5c03</citedby><cites>FETCH-LOGICAL-c758t-51a924702b5cd9a16aa4b13b8756392d7c0eaf53abf02f597312abdcbc7ca5c03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216112/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216112/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25360599$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Gross, Robert E.</contributor><creatorcontrib>Martinez-Ramirez, Daniel</creatorcontrib><creatorcontrib>Morishita, Takashi</creatorcontrib><creatorcontrib>Zeilman, Pamela R</creatorcontrib><creatorcontrib>Peng-Chen, Zhongxing</creatorcontrib><creatorcontrib>Foote, Kelly D</creatorcontrib><creatorcontrib>Okun, Michael S</creatorcontrib><title>Atrophy and other potential factors affecting long term deep brain stimulation response: a case series</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To describe three DBS cases which presented with new side effects or loss of benefit from stimulation after long-term follow-up and to discuss the potential contributing factors.
A University of Florida (UF) database (INFORM) search was performed, identifying three patients, two Parkinson's disease (PD) and one Essential Tremor (ET), with an unexpected change in long-term programming thresholds as compared to initial evaluation. Clinical follow-up, programming, imaging studies, and lead measurements were reviewed. The UF Institutional Review Board (IRB) approved this study.
A substantial increase in the 3rd ventricular width (120%), Evans index (6%), ventricular index (5%), and cella media index (17%) was uncovered. A change in thresholds across lead contacts with a decrease in current densities as well as a relative lateral change of lead location was also observed. Hardware-related complications, lead migration, and impedance variability were not identified.
Potential factors contributing to long-term side effects should be examined during a DBS troubleshooting assessment. Clinicians should be aware that in DBS therapy there is delivery of electricity to a changing brain, and atrophy may possibly affect DBS programming settings as part of long-term follow-up.</description><subject>Age</subject><subject>Aged</subject><subject>Aging</subject><subject>Atrophy</subject><subject>Biology and Life Sciences</subject><subject>Brain</subject><subject>Brain - pathology</subject><subject>Cerebral Ventricles - pathology</subject><subject>Comparative analysis</subject><subject>Complications</subject><subject>Data bases</subject><subject>Deep Brain Stimulation</subject><subject>Electric contacts</subject><subject>Electrodes</subject><subject>Female</subject><subject>Humans</subject><subject>Identification methods</subject><subject>Lead</subject><subject>Magnetic Resonance Imaging</subject><subject>Maintenance</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Migration</subject><subject>Movement disorders</subject><subject>Neurodegenerative diseases</subject><subject>Neuroimaging</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Organ Size</subject><subject>Parkinson's disease</subject><subject>Parkinsons disease</subject><subject>Patients</subject><subject>Programming</subject><subject>Risk Factors</subject><subject>Side effects</subject><subject>Stimulation</subject><subject>Surgery</subject><subject>Thresholds</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Tremor</subject><subject>Ventricle</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1uL1DAUx4so7jr6DUQDgujDjLk0vfggDIuXgYUFb6_hNE1mMqRNN0nF_fZmnO4ylX2QQhKS3_nn5N9zsuw5wSvCSvJu70bfg10NrlcrTAjhBXmQnZOa0WVBMXt4sj7LnoSwx5izqigeZ2eUswLzuj7P9Dp6N-xuEPQtcnGnPBpcVH00YJEGGZ0PCLRWMpp-i6xLQ1S-Q61SA2o8mB6FaLrRQjSuR16FlFBQ7xEgCUGhoLxR4Wn2SIMN6tk0L7Ifnz5-v_iyvLz6vLlYXy5lyau45ARqmpeYNly2NZACIG8Ia6qSF6ymbSmxAs0ZNBpTzeuSEQpNKxtZSuASs0X28qg7WBfEZFEQpCA1rliF80RsjkTrYC8GbzrwN8KBEX83nN8K8NFIq0SLK1wQreuC1rkq2oY2kNzUbZpwjVnS-jDdNjadamWyzYOdic5PerMTW_dL5DRlRGgSeDMJeHc9qhBFZ4JU1kKv3HjIm2JMc1bWCX31D3r_6yZqC-kBptcu3SsPomKdk5LkHCcnF9nqHip9reqMTPWkTdqfBbydBSQmqt9xC2MIYvPt6_-zVz_n7OsTdqfAxl1wdjyUUpiD-RGU3oXglb4zmWBxaIdbN8ShHcTUDinsxekPugu6rX_2B3AVBZ8</recordid><startdate>20141031</startdate><enddate>20141031</enddate><creator>Martinez-Ramirez, Daniel</creator><creator>Morishita, Takashi</creator><creator>Zeilman, Pamela R</creator><creator>Peng-Chen, Zhongxing</creator><creator>Foote, Kelly D</creator><creator>Okun, Michael S</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20141031</creationdate><title>Atrophy and other potential factors affecting long term deep brain stimulation response: a case series</title><author>Martinez-Ramirez, Daniel ; Morishita, Takashi ; Zeilman, Pamela R ; Peng-Chen, Zhongxing ; Foote, Kelly D ; Okun, Michael S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c758t-51a924702b5cd9a16aa4b13b8756392d7c0eaf53abf02f597312abdcbc7ca5c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Age</topic><topic>Aged</topic><topic>Aging</topic><topic>Atrophy</topic><topic>Biology and Life Sciences</topic><topic>Brain</topic><topic>Brain - pathology</topic><topic>Cerebral Ventricles - pathology</topic><topic>Comparative analysis</topic><topic>Complications</topic><topic>Data bases</topic><topic>Deep Brain Stimulation</topic><topic>Electric contacts</topic><topic>Electrodes</topic><topic>Female</topic><topic>Humans</topic><topic>Identification methods</topic><topic>Lead</topic><topic>Magnetic Resonance Imaging</topic><topic>Maintenance</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Migration</topic><topic>Movement disorders</topic><topic>Neurodegenerative diseases</topic><topic>Neuroimaging</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Organ Size</topic><topic>Parkinson's disease</topic><topic>Parkinsons disease</topic><topic>Patients</topic><topic>Programming</topic><topic>Risk Factors</topic><topic>Side effects</topic><topic>Stimulation</topic><topic>Surgery</topic><topic>Thresholds</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Tremor</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martinez-Ramirez, Daniel</creatorcontrib><creatorcontrib>Morishita, Takashi</creatorcontrib><creatorcontrib>Zeilman, Pamela R</creatorcontrib><creatorcontrib>Peng-Chen, Zhongxing</creatorcontrib><creatorcontrib>Foote, Kelly D</creatorcontrib><creatorcontrib>Okun, Michael S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martinez-Ramirez, Daniel</au><au>Morishita, Takashi</au><au>Zeilman, Pamela R</au><au>Peng-Chen, Zhongxing</au><au>Foote, Kelly D</au><au>Okun, Michael S</au><au>Gross, Robert E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atrophy and other potential factors affecting long term deep brain stimulation response: a case series</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2014-10-31</date><risdate>2014</risdate><volume>9</volume><issue>10</issue><spage>e111561</spage><epage>e111561</epage><pages>e111561-e111561</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To describe three DBS cases which presented with new side effects or loss of benefit from stimulation after long-term follow-up and to discuss the potential contributing factors.
A University of Florida (UF) database (INFORM) search was performed, identifying three patients, two Parkinson's disease (PD) and one Essential Tremor (ET), with an unexpected change in long-term programming thresholds as compared to initial evaluation. Clinical follow-up, programming, imaging studies, and lead measurements were reviewed. The UF Institutional Review Board (IRB) approved this study.
A substantial increase in the 3rd ventricular width (120%), Evans index (6%), ventricular index (5%), and cella media index (17%) was uncovered. A change in thresholds across lead contacts with a decrease in current densities as well as a relative lateral change of lead location was also observed. Hardware-related complications, lead migration, and impedance variability were not identified.
Potential factors contributing to long-term side effects should be examined during a DBS troubleshooting assessment. Clinicians should be aware that in DBS therapy there is delivery of electricity to a changing brain, and atrophy may possibly affect DBS programming settings as part of long-term follow-up.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>25360599</pmid><doi>10.1371/journal.pone.0111561</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2014-10, Vol.9 (10), p.e111561-e111561 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1619083804 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS) Journals Open Access; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Age Aged Aging Atrophy Biology and Life Sciences Brain Brain - pathology Cerebral Ventricles - pathology Comparative analysis Complications Data bases Deep Brain Stimulation Electric contacts Electrodes Female Humans Identification methods Lead Magnetic Resonance Imaging Maintenance Male Medicine Medicine and Health Sciences Middle Aged Migration Movement disorders Neurodegenerative diseases Neuroimaging Neurology Neurosurgery NMR Nuclear magnetic resonance Organ Size Parkinson's disease Parkinsons disease Patients Programming Risk Factors Side effects Stimulation Surgery Thresholds Time Factors Treatment Outcome Tremor Ventricle |
| title | Atrophy and other potential factors affecting long term deep brain stimulation response: a case series |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T10%3A37%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Atrophy%20and%20other%20potential%20factors%20affecting%20long%20term%20deep%20brain%20stimulation%20response:%20a%20case%20series&rft.jtitle=PloS%20one&rft.au=Martinez-Ramirez,%20Daniel&rft.date=2014-10-31&rft.volume=9&rft.issue=10&rft.spage=e111561&rft.epage=e111561&rft.pages=e111561-e111561&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0111561&rft_dat=%3Cgale_plos_%3EA417145056%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1619083804&rft_id=info:pmid/25360599&rft_galeid=A417145056&rft_doaj_id=oai_doaj_org_article_d08061ff96294e6db2ba620fdba60903&rfr_iscdi=true |