Myxomavirus anti-inflammatory chemokine binding protein reduces the increased plaque growth induced by chronic Porphyromonas gingivalis oral infection after balloon angioplasty aortic injury in mice

Thrombotic occlusion of inflammatory plaque in coronary arteries causes myocardial infarction. Treatment with emergent balloon angioplasty (BA) and stent implant improves survival, but restenosis (regrowth) can occur. Periodontal bacteremia is closely associated with inflammation and native arterial...

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Veröffentlicht in:	PloS one 2014-10, Vol.9 (10), p.e111353-e111353
Hauptverfasser:	Lucas, Alexandra R, Verma, Raj K, Dai, Erbin, Liu, Liying, Chen, Hao, Kesavalu, Sheela, Rivera, Mercedes, Velsko, Irina, Ambadapadi, Sriram, Chukkapalli, Sasanka, Kesavalu, Lakshmyya
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha 1-Antitrypsin - pharmacology alpha 1-Antitrypsin - therapeutic use Angioplasty Angioplasty, Balloon - adverse effects Animal models Animals Aorta Aorta - drug effects Aorta - surgery Apolipoprotein E Arteries Arteriosclerosis Atherosclerosis Bacteremia Bacterial infections Bacteroidaceae Infections - complications Bacteroidaceae Infections - drug therapy Balloon treatment Cardiovascular disease Chemokine-binding protein Chemokines Chronic infection Coronary artery CXC chemokines Dental plaque Dental Plaque - drug therapy Dental Plaque - microbiology Dentistry Departments Diabetes Glycoproteins Heart diseases IgG antibody Immunoglobulin G Implants Infections Inflammation Lymphocytes Medicine Medicine and Health Sciences Mice Monocytes MyD88 protein Myocardial infarction Occlusion Oral infection Periodontics Plaque, Atherosclerotic - drug therapy Plaque, Atherosclerotic - microbiology Porphyromonas gingivalis Porphyromonas gingivalis - pathogenicity Protease Proteinase inhibitors Proteins Receptors, Interferon - therapeutic use Regrowth Restenosis Rodents Serine Serine proteinase Stents Surgical implants Survival Systematic review Thrombolysis Transplants & implants Vasculitis Viral Proteins - pharmacology Viral Proteins - therapeutic use Virology Viruses
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