Characterization of the highly variable immune response gene family, He185/333, in the sea urchin, Heliocidaris erythrogramma

This study characterizes the highly variable He185/333 genes, transcripts and proteins in coelomocytes of the sea urchin, Heliocidaris erythrogramma. Originally discovered in the purple sea urchin, Strongylocentrotus purpuratus, the products of this gene family participate in the anti-pathogen defen...

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Veröffentlicht in:	PloS one 2014-10, Vol.9 (10), p.e62079-e62079
Hauptverfasser:	Roth, Mattias O, Wilkins, Adam G, Cooke, Georgina M, Raftos, David A, Nair, Sham V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptations Animals Base Sequence Bioinformatics Chemical properties Codons Coelomocytes Diversification Echinoidea Evolution Gene sequencing Genes Genes, MHC Class II Genetic Variation Genomes Homology Hypothesis testing Immune response Immune system Immunofluorescence Immunology Introns Introns - genetics Microscopy Molecular biology Multigene Family Oligomerization Open reading frames Pathogens Phylogenetics Post-translation Proteins Sea Urchins - genetics Sea Urchins - immunology Sequence Alignment Signal transduction Single nucleotide polymorphisms Single-nucleotide polymorphism Species Specificity Subpopulations Western blotting
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