Anti-inflammatory properties of the medicinal mushroom Cordyceps militaris might be related to its linear (1→3)-β-D-glucan

The Ascomycete Cordyceps militaris, an entomopathogenic fungus, is one of the most important traditional Chinese medicines. Studies related to its pharmacological properties suggest that this mushroom can exert interesting biological activities. Aqueous (CW and HW) and alkaline (K5) extracts contain...

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Veröffentlicht in:	PloS one 2014-10, Vol.9 (10), p.e110266-e110266
Hauptverfasser:	Smiderle, Fhernanda R, Baggio, Cristiane H, Borato, Débora G, Santana-Filho, Arquimedes P, Sassaki, Guilherme L, Iacomini, Marcello, Van Griensven, Leo J L D
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-inflammatory agents Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology beta-Glucans - chemistry beta-Glucans - pharmacology Biochemistry Biological Products - chemistry Biological Products - pharmacology Biology and Life Sciences Cordyceps - chemistry Cordyceps militaris Cyclooxygenase 2 - metabolism Cyclooxygenase-2 Engineering and Technology Entomopathogenic fungi Gene expression Glucan Herbal medicine Humans IL-1β Immune system Inflammation Inhibition Interleukin-1beta - metabolism Leukocyte migration Leukocytes Leukocytes (neutrophilic) Lipopolysaccharides Macrophages Macrophages - drug effects Macrophages - metabolism Magnetic resonance spectroscopy Medicine and health sciences Molecular biology Mushrooms NMR Nuclear magnetic resonance Pain Pain perception Pharmacology Polysaccharides Proteoglycans Research and Analysis Methods Saccharides Spectrometry Traditional Chinese medicine Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-α White blood cells
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