Revealing a brain network endophenotype in families with idiopathic generalised epilepsy

Idiopathic generalised epilepsy (IGE) has a genetic basis. The mechanism of seizure expression is not fully known, but is assumed to involve large-scale brain networks. We hypothesised that abnormal brain network properties would be detected using EEG in patients with IGE, and would be manifest as a...

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Veröffentlicht in:	PloS one 2014-10, Vol.9 (10), p.e110136-e110136
Hauptverfasser:	Chowdhury, Fahmida A, Woldman, Wessel, FitzGerald, Thomas H B, Elwes, Robert D C, Nashef, Lina, Terry, John R, Richardson, Mark P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Biology and Life Sciences Brain Brain - metabolism Brain - physiopathology Clustering Computer and Information Sciences EEG Electroencephalography Endophenotypes Engineering schools Epilepsy Epilepsy, Generalized - diagnosis Epilepsy, Generalized - drug therapy Epilepsy, Generalized - etiology Factor analysis Female Frequencies Graph theory Humans Male Medical imaging Medicine and Health Sciences Middle Aged Network topologies Neurosciences Patients Physical Sciences Psychiatry Seizures Seizures (Medicine) Topology Young Adult
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