FGF8 activates proliferation and migration in mouse post-natal oligodendrocyte progenitor cells

Fibroblast growth factor 8 (FGF8) is a key molecular signal that is necessary for early embryonic development of the central nervous system, quickly disappearing past this point. It is known to be one of the primary morphogenetic signals required for cell fate and survival processes in structures su...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e108241
Hauptverfasser:	Cruz-Martinez, Pablo, Martinez-Ferre, Almudena, Jaramillo-Merchán, Jesus, Estirado, Alicia, Martinez, Salvador, Jones, Jonathan
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animal models Animals Animals, Newborn Anticoagulants Beads Biology and Life Sciences Biomarkers Cell activation Cell culture Cell Differentiation - drug effects Cell Differentiation - genetics Cell fate Cell migration Cell Movement - drug effects Cell Movement - genetics Cell proliferation Cell Proliferation - drug effects Cell survival Cells (biology) Central nervous system Cerebellum Demyelinating Diseases - therapy Demyelination Developmental stages Embryogenesis Embryonic growth stage Experiments Fibroblast growth factor 8 Fibroblast Growth Factor 8 - pharmacology Fibroblasts Gene expression Glial stem cells Growth factors Heparin Immunocytochemistry Kinases Leukodystrophy Metabolism Mice Multiple sclerosis Nervous system Neural Stem Cells - cytology Neural Stem Cells - drug effects Neural Stem Cells - metabolism Neurosciences Oligodendroglia - cytology Oligodendroglia - metabolism Penicillin Progenitor cells Research and Analysis Methods Stem Cell Transplantation Stem cells Telencephalon
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