Galectin-3 as a marker and potential therapeutic target in breast cancer

Galectin-3 has a relatively high level of expression in triple-negative breast cancers and is a potential marker for this disease. However, the clinical and prognostic implications of galectin-3 expression in breast cancer remain unclear. We examined mastectomy specimens from 1086 breast cancer case...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e103482
Hauptverfasser:	Zhang, Hao, Luo, Minna, Liang, Xi, Wang, Dan, Gu, Xin, Duan, Chao, Gu, Huizi, Chen, Guanglei, Zhao, Xinhan, Zhao, Zuowei, Liu, Caigang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Apoptosis Apoptosis - drug effects Arsenic Arsenic Trioxide Arsenicals - pharmacology Biomarkers, Tumor - deficiency Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cell cycle Cell growth Cell Line, Tumor Chemoresistance Chemotherapy Development and progression Drug Resistance, Neoplasm Female Galectin 3 - deficiency Galectin 3 - genetics Galectin 3 - metabolism Galectin-3 Gene expression Gene Expression Regulation, Neoplastic - drug effects Gene Knockdown Techniques Health aspects Hospitals Humans Immunohistochemistry Killing Medical prognosis Medicine and Health Sciences Molecular Targeted Therapy Multiple myeloma Nitric oxide Oxides - pharmacology Prognosis Regression analysis RNA, Small Interfering - genetics Studies Surgery Survival Analysis Tissues Tumors
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