Plasma components and platelet activation are essential for the antimicrobial properties of autologous platelet-rich plasma: an in vitro study

Autologous platelet concentrates are successfully adopted in a variety of medical fields to stimulate bone and soft tissue regeneration. The rationale for their use consists in the delivery of a wide range of platelet-derived bioactive molecules that promotes wound healing. In addition, antimicrobia...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e107813-e107813
Hauptverfasser:	Drago, Lorenzo, Bortolin, Monica, Vassena, Christian, Romanò, Carlo L, Taschieri, Silvio, Del Fabbro, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Anti-Bacterial Agents - pharmacology Antibacterial activity Antibacterial agents Anticoagulants Antimicrobial activity Antimicrobial agents Bacteria Biology and Life Sciences Blood platelets Bone growth Coagulation Enterococcus faecalis Enterococcus faecalis - drug effects Enterococcus faecalis - physiology Gene expression Gram-positive bacteria Growth factors Humans Laboratories Medicine and Health Sciences Microbial Sensitivity Tests Microbial Viability Minimum inhibitory concentration Mouth - microbiology Oral cavity Peptides Plasma Platelet Activation Platelet-Rich Plasma - cytology Platelets Pneumonia Regeneration Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - physiology Staphylococcus infections Streptococcus Streptococcus agalactiae Streptococcus agalactiae - drug effects Streptococcus agalactiae - physiology Streptococcus infections Streptococcus oralis - drug effects Streptococcus oralis - physiology Surgery Tissue engineering Wound healing
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