Association of promoter methylation of RUNX3 gene with the development of esophageal cancer: a meta analysis

Runt-related transcription factor 3 (RUNX3) is a member of the runt-domain family of transcription factors. Emerging evidence indicates that RUNX3 is a tumor suppressor gene in several types of human cancers including esophageal cancer. However, the association between RUNX3 promoter methylation and...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e107598
Hauptverfasser:	Wang, Yi, Qin, Xiuguang, Wu, Jieqing, Qi, Bo, Tao, Yipeng, Wang, Wenju, Liu, Fulei, Li, Hanchen, Zhao, Baosheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Cancer Carcinogenesis Carcinogens Cell cycle Cell Transformation, Neoplastic - genetics Core Binding Factor Alpha 3 Subunit - genetics Data processing Deactivation Disease Progression DNA Methylation Esophageal cancer Esophageal Neoplasms - genetics Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophagus Gastric cancer Gene Expression Regulation, Neoplastic Genes Genetic Association Studies Humans Inactivation Lesions Lymph nodes Medical prognosis Medicine and Health Sciences Meta-analysis Methylation Mucosa Prognosis Promoter Regions, Genetic Publication Bias Quality Runx3 gene Runx3 protein Squamous cell carcinoma Stomach cancer Studies Surgery Survival Thoracic surgery Transcription factors Tumor suppressor genes Tumorigenesis
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