Correlation of Klebsiella pneumoniae comparative genetic analyses with virulence profiles in a murine respiratory disease model

Klebsiella pneumoniae is a bacterial pathogen of worldwide importance and a significant contributor to multiple disease presentations associated with both nosocomial and community acquired disease. ATCC 43816 is a well-studied K. pneumoniae strain which is capable of causing an acute respiratory dis...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e107394-e107394
Hauptverfasser:	Fodah, Ramy A, Scott, Jacob B, Tam, Hok-Hei, Yan, Pearlly, Pfeffer, Tia L, Bundschuh, Ralf, Warawa, Jonathan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal models Animals Antibiotics Bacterial Proteins - genetics Base Sequence Biochemistry Biology Biology and Life Sciences Cancer Catabolism Cell culture Cell Line Cell lines Clinical isolates Conservation CRISPR Disease Models, Animal DNA, Bacterial - genetics Gene sequencing Genetic analysis Genome, Bacterial - genetics Genomes Genomics Glycerol Hematology Hospitals Identification Immunology Infections Internal medicine Klebsiella Klebsiella Infections - microbiology Klebsiella pneumoniae Klebsiella pneumoniae - genetics Macrophages Macrophages - microbiology Medicine Medicine and Health Sciences Mice Mice, Inbred BALB C Molecular Sequence Data Nosocomial infection Pathogens Pneumonia Research and Analysis Methods Respiratory diseases Respiratory Tract Diseases - microbiology Secretion Sequence Analysis, DNA - methods Strains (organisms) Urogenital system Virulence Virulence (Microbiology) Virulence - genetics Virulence Factors - genetics
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