Characterization of a spontaneous retinal neovascular mouse model

Vision loss due to vascular disease of the retina is a leading cause of blindness in the world. Retinal angiomatous proliferation (RAP) is a subgroup of neovascular age-related macular degeneration (AMD), whereby abnormal blood vessels develop in the retina leading to debilitating vision loss and ev...

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Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e106507-e106507
Hauptverfasser:	Hasegawa, Eiichi, Sweigard, Harry, Husain, Deeba, Olivares, Ana M, Chang, Bo, Smith, Kaylee E, Birsner, Amy E, D'Amato, Robert J, Michaud, Norman A, Han, Yinan, Vavvas, Demetrios G, Miller, Joan W, Haider, Neena B, Connor, Kip M
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Angiogenesis Angiography Animals Biology and Life Sciences Blindness Blood vessels Chemical properties Confocal microscopy Diabetic retinopathy Disease Disease Models, Animal Edema Enzyme-Linked Immunosorbent Assay Epithelium Fluorescein Fluorescein Angiography Image analysis Image processing Image reconstruction Laboratories Lesions Longitudinal Studies Macular degeneration Medical schools Medicine and Health Sciences Mice Microscopic analysis Microscopy Optical Coherence Tomography Photography Photoreceptors Physicians Pigment Epithelium of Eye - pathology Research and Analysis Methods Retina Retina - pathology Retinal Neovascularization - pathology Retinal pigment epithelium Three dimensional analysis Tomography, Optical Coherence Vascular diseases Vascular endothelial growth factor Vascularization Vision
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