Col6a1 null mice as a model to study skin phenotypes in patients with collagen VI related myopathies: expression of classical and novel collagen VI variants during wound healing

Patients suffering from collagen VI related myopathies caused by mutations in COL6A1, COL6A2 and COL6A3 often also display skin abnormalities, like formation of keloids or "cigarette paper" scars, dry skin, striae rubrae and keratosis pilaris (follicular keratosis). Here we evaluated if Co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-08, Vol.9 (8), p.e105686
Hauptverfasser:	Lettmann, Sandra, Bloch, Wilhelm, Maaß, Tobias, Niehoff, Anja, Schulz, Jan-Niklas, Eckes, Beate, Eming, Sabine A, Bonaldo, Paolo, Paulsson, Mats, Wagener, Raimund
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animals Biochemistry Biology and Life Sciences Biomechanics Bleomycin Cells, Cultured Chains Collagen Collagen Type VI - analysis Collagen Type VI - genetics Collagen Type VI - ultrastructure Congenital diseases Dermatology Disease Models, Animal Extracellular matrix Female Fibrosis Gene Deletion Gene expression Gene Expression Regulation Genetic aspects Keratosis Laboratory animals Medical research Medicine Mice Mice, Inbred C57BL Morphology Muscles Muscular Diseases - genetics Muscular Diseases - pathology Muscular dystrophy Mutation Myopathy Pathogenesis Pathology Patients Proteins Research and Analysis Methods Rodents Scars Skin Skin - metabolism Skin - pathology Skin - ultrastructure Studies Tensile Strength Wound care Wound Healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!