Generation and behavior characterization of CaMKIIβ knockout mice

The calcium/calmodulin-dependent protein kinase II (CaMKII) is abundant in the brain, where it makes important contributions to synaptic organization and homeostasis, including playing an essential role in synaptic plasticity and memory. Four genes encode isoforms of CaMKII (α, β, δ, γ), with CaMKII...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-08, Vol.9 (8), p.e105191-e105191
Hauptverfasser:	Bachstetter, Adam D, Webster, Scott J, Tu, Tao, Goulding, Danielle S, Haiech, Jacques, Watterson, D Martin, Van Eldik, Linda J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Alzheimer's disease Alzheimers disease Animals Anxiety Anxiety - enzymology Ataxia Ataxia - enzymology Behavior Behavioral plasticity Biology and Life Sciences Body Composition Body mass Brain Ca2+/calmodulin-dependent protein kinase II Calcium Calcium-binding protein Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism Calmodulin Cloning Cognition Cognition Disorders - enzymology Cognitive ability Field tests Functional anatomy Genotypes Grip strength Homeostasis Isoforms Kinases Laboratory animals Male Memory Mice, Inbred C57BL Mice, Knockout Muscle Strength Nesting Behavior Neurosciences Object recognition Pattern recognition Pattern Recognition, Physiological Plasticity Proteins Research and Analysis Methods Rodents Rotarod Performance Test Structure-function relationships Synaptic plasticity Transgenic animals Weaning Weight Gain Wheel running
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!