ATO/ATRA/anthracycline-chemotherapy sequential consolidation achieves long-term efficacy in primary acute promyelocytic leukemia

The combination of all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3, ATO) has been effective in obtaining high clinical complete remission (CR) rates in acute promyelocytic leukemia (APL), but the long-term efficacy and safety among newly diagnosed APL patients are unclear. In this retrosp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-08, Vol.9 (8), p.e104610
Hauptverfasser:	Long, Zi-Jie, Hu, Yuan, Li, Xu-Dong, He, Yi, Xiao, Ruo-Zhi, Fang, Zhi-Gang, Wang, Dong-Ning, Liu, Jia-Jun, Yan, Jin-Song, Huang, Ren-Wei, Lin, Dong-Jun, Liu, Quentin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acute myelocytic leukemia Acute promyeloid leukemia Adolescent Adult Anthracycline Anthracyclines - administration & dosage Anthracyclines - adverse effects Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Arsenic Arsenic trioxide Arsenicals - administration & dosage Arsenicals - adverse effects Blood Bone marrow Chemotherapy Child Consolidation Consolidation Chemotherapy - adverse effects Consolidation Chemotherapy - methods Disease Disease-Free Survival Effectiveness Female Hematology Hospitals Humans Induction therapy Leukemia Leukemia, Promyelocytic, Acute - drug therapy Lymphocyte receptors Male Medicine and Health Sciences Middle Aged Neoplasm Recurrence, Local - drug therapy Oxides - administration & dosage Oxides - adverse effects Patients Promyeloid leukemia Remission Remission Induction - methods Retinoic acid Retrospective Studies Stem cells Survival Toxicity Transplants & implants Treatment Outcome Tretinoin Tretinoin - administration & dosage Tretinoin - adverse effects Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!